Sporadic and MEN1-related gastrinoma and Zollinger Ellison syndrome: Differences in clinical manifestation and severity

#3364

Introduction: Zollinger-Ellison syndrome (ZES) associated with gastrinoma may be sporadic (Sp), but in 25% of the cases is part of the inherited multiple endocrine neoplasia 1 (MEN1) syndrome. Data comparing Sp and MEN1/ZES forms are scanty.

Aim(s): To compare the clinical characteristics of Sp and MEN1/ZES.

Materials and methods: Between 1995-2020, all ZES patients were evaluated at Ospedale Maggiore Policlinico, Milan.

Conference:

Presenting Author: Rossi R

Authors: Massironi S, Rossi R, Eller-Vainicher C, Cavalcoli F, Ciafardini C,

Keywords: gastrinoma, zollinger ellison syndrome, multiple endocrine neoplasia 1 (MEN1) syndrome,