Transformation to High Grade 3 (G3) Neuroendocrine Neoplasia (NEN) – Molecular Imaging, Pathologic Features and Patient Outcomes
Introduction: Transformation of lower grade to Grade 3 (G3) NEN potentially impacts prognosis & treatment options.
Aim(s): We assessed PET imaging & pathologic features and outcome of such patients (pts).
Materials and methods: Retrospective review of pts with biopsy-proven G3 progression. 68Ga-DOTATATE (GaTate) and 18F-fluorodeoxyglucose (FDG) PET/CT and immunohistochemistry (IHC) results (p53 and Rb) were evaluated.
Conference: 17th Annual ENETSConcerence (2020)
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