Vitamin D Deficiency as a Risk Factor in Pancreatic Neuroendocrine Neoplasms: Report from a Series at a Single Institute

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Introduction: Vitamin D deficiency (VitDdef) is hypothesized to represent a risk factor in several neoplasms. To date, vitamin D levels have not been previously evaluated in patients with pancreatic neuroendocrine neoplasms (pNENs).

Aim(s): To determine whether VitDdef may represent a risk factor for pNENs and may be associated with overall survival (OS) and progression-free survival (PFS).

Materials and methods: From September 2009 to September 2014 pNEN was newly diagnosed in 47 patients (F= 30, median age 61 yrs). Grading was G1, G2 and G3 in 32, 14 and one patient, respectively. Again, TNM stage was I, II, III and IV in 16, 17, 2 and 12 cases, respectively. Serum 25-hydroxyvitamin D (25OHvitD) levels were measured at baseline in all the patients and its deficiency was defined when facing with values

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Zilli A, Fanetti I, Cavalcoli F, Conte D, Ciafardini C,

Keywords: pancreatic neuroendocrine tumor, 25OHvitamin D,