Abstract Library

#1317 Value of Octreoscan and 18FDG-PET for Clinical Prognosis of Patients with Neuroendocrine Neoplasms

Introduction: Despite the existence of biological markers of aggressiveness, the clinical course of gastro-entero-pancreatic (GEP) neuroendocrine neoplasms (NEN) remains difficult to predict. Discrepancies between imaging data generated with 111In-pentetreotide scintigraphy (SRS) and 18 F-FDG-PET could reflect the degree of cellular de-differentiation.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Gouffon M

Authors: Gouffon M, Prior J, Ratib O, Krause T, Pralong F,

Keywords: 111In-pentetreotide scintigraphy, 18F-FDG-PET, prognosis, clinical course,

#760 Intraoperative Gamma Probe Detection of Metastatic Medullary Thyroid Carcinoma (MTC) with 111In-Pentetreotide

Introduction: MTC is a rare thyroid malignancy representing approximately 5-10% of all thyroid tumors. Early diagnosis and radical surgery are essential to reduce the morbidity and mortality associated with MTC. Somatostatin receptors (SSTRs) expression has been described in MTC with a variable pattern, SSTR2 being prevalent. Although somatostatin analogues demonstrated poor efficacy in the control of MTC growth, SSTR expression can be useful in Nuclear Medicine diagnostic procedures. 111In-pentetreotide scintigraphy and 68Ga-somatostatin analogues PET-CT represent valuable techniques in the detection of MTC, although with a lower sensitivity compared to 18F-DOPA PET-CT.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Iacovazzo D, Piacentini S, Lugli F, Fusco A, Perotti G,

Keywords: mtc, srs,