Abstract Library
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#3691 Efficacy of 177Lu-octreotate in biliary duct neuroendocrine tumor
Introduction: We report the case of a 69-year-old woman presenting a biliary duct neuroendocrine tumor, diagnosed in 2003 treated by extrahepatic biliary tract resection.
Conference:
Presenting Author:
Authors: Kelly A, Otman H, Petorin C, Perret-Boire S, Chanchou M,
Keywords: 177Lu-octreotate, biliary duct neuroendocrine tumor,
Introduction: PRRT has shown favourable results in NETs. Long-term safety and efficacy data for 177Lu-Octreotate PRRT, particularly in combination with chemotherapy, is lacking.
Conference:
Presenting Author: Ransom D
Authors: Ransom D, Kennedy K, Turner J, Macdonald W, Boardman G,
Keywords: PRRT, long term, chemotherapy, leukaemia, myelodysplasia, renal,
Introduction: The control of hypoglycemic hyperinsulinemic syndrome from malignant insulinoma is challenging because it is often refractory to diazoxide and somatostatin analogues (SA). Everolimus can have side effects that can limit its use. Pasireotide, a multi-receptor-targeted SA with a high binding affinity to SSTR1 and SSTR5, exhibits a strong inhibitory effect of insulin secretion.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Davi' M
Authors: Zambon G, Cosaro E, Cingarlini S, Trombetta M, Landoni L,
Keywords: pasireotide, malignant insulinoma, hypoglycemia,
Introduction: Paragangliomas (PGL) are a heterogeneous group of rare tumours that can express high numbers of somatostatin receptors on their cell surface and can be targeted with peptide receptor radionuclide therapy (PRRT) using the radiolabelled somatostatin analogue [lutetium-177-DOTA-Tyr3-]octreotate (177Lu-octreotate).
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Smit Duijzentkunst D
Authors: Smit Duijzentkunst D, Kwekkeboom D,
Keywords: PRRT, paragangliomas,
Introduction: Although somatostatin analogues (SSA) and peptide receptor radionuclide therapy with 177Lu-octreotate (PRRT) are validated therapies in patients with advanced metastatic neuroendocrine tumours, it is still unclear if the combined therapy with PRRT and SSA can provide a prolonged survival compared to patients treated with PRRT alone.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Yordanova A
Authors: Yordanova A, Wicharz M, Gonzalez-Carmona M, Strassburg C, Mayer K,
Keywords: PRRT, SSA, combined therapy, survival,