Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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#3613 Plasma-derived small extracellular vesicles reveal pancreatic neuroendocrine tumors

Introduction: The incidence of pancreatic neuroendocrine tumors (PNETs) has increased over the past 30 years worldwide. The survival rate is low due to the diagnosis being done at a higher stage and unavailability of specific and sensitive diagnostic markers. Hence, better and efficient early diagnostic biomarkers are required at the earliest. As the role of small extracellular vesicles (sEV) in tumor growth and cancer metastasis is increasing exponentially due to its capability to cause metastasis and proliferation. For the first time, this study establishes the relationship between sEV concentration and PNET grades as well as the presence of BIRC2/cIAP as sEV cargo derived from plasma.

Conference:

Presenting Author: Gorai P

Authors: Gorai P, Rastogi S, Soni P, Singh S, Agarwal S,

Keywords: pancreatic neuroendocrine tumor, small extracellular vesicles, BIRC2/cIAP, early diagnostic biomarker,

#3174 Utility and timing of Technetium-99m-diethylene-triamine-penta-acetic acid measurement of glomerular filtration rate in patients undergoing peptide receptor radionuclide therapy

Introduction: Renal toxicity is a potential side effect of Lutetium-177 Peptide Receptor Radionuclide Therapy (177Lu-PRRT). Some centres use serial Technetium-99m-diethylene-triaminepentaacetic acid (99mTc-DTPA) glomerular filtration rate (GFR) measurements to detect early renal toxicity, but there is no consensus regarding the timing of serial scans nor its utility.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Agarwal V, Gordon S, Bailey D, Pavlakis N, Aslani A,

Keywords: Technetium-99m-diethylene-triaminepentaacetic acid (99mTc-DTPA) glomerular filtration rate (GFR), Lutetium-177 Peptide Receptor Radionuclide Therapy (177Lu-PRRT),