Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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#3680 18F-FMISO PET in metastatic neuroendocrine neoplasms – A pilot study

Introduction: The phenomenon of peripheral 68Ga-DOTATATE avidity without central avidity (a so-called “donut") has been observed in neuroendocrine neoplasm (NEN) lesions. There has been speculation as to whether this region of non-avidity reflects hypoxia, de-differentiated disease or other causes. The presence of hypoxia has significant prognostic and therapeutic implications, and was evaluated in these lesions using 18F-FMISO PET/CT.

Conference:

Presenting Author: Chan D

Authors: Chan D, Conner A, Pavlakis N, Bailey E, Aslani A,

Keywords: hypoxia, 18F-FMISO, 68Ga-DOTATATE, PET/CT, biomarker,

#3451 Peptide Receptor Radionuclide Therapy (PRRT) and impact on quality of life in patients with neuroendocrine neoplasms: An international multi-centre study

Introduction: Neuroendocrine neoplasms (NENs) affect health-related quality of life (HRQOL) due to tumor burden, hormone-secretory symptoms, and treatment-related side effects.

Conference:

Presenting Author: Kong G

Authors: Kong G, Corsini N, Hogg A, Mercurio J, Bailey D,

Keywords: PRRT, HRQOL, Neuroendocrine neoplasm, Multi-centre study, QLQ-C30,

#3174 Utility and timing of Technetium-99m-diethylene-triamine-penta-acetic acid measurement of glomerular filtration rate in patients undergoing peptide receptor radionuclide therapy

Introduction: Renal toxicity is a potential side effect of Lutetium-177 Peptide Receptor Radionuclide Therapy (177Lu-PRRT). Some centres use serial Technetium-99m-diethylene-triaminepentaacetic acid (99mTc-DTPA) glomerular filtration rate (GFR) measurements to detect early renal toxicity, but there is no consensus regarding the timing of serial scans nor its utility.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Agarwal V, Gordon S, Bailey D, Pavlakis N, Aslani A,

Keywords: Technetium-99m-diethylene-triaminepentaacetic acid (99mTc-DTPA) glomerular filtration rate (GFR), Lutetium-177 Peptide Receptor Radionuclide Therapy (177Lu-PRRT),

#1311 Blood-Based Prognostic Biomarkers in Neuroendocrine Tumour: A Retrospective Study

Introduction: Markers of systemic inflammation –such as the neutrophil:lymphocyte ratio (NLR), platelet:lymphocyte ratio (PLR) and lymphocyte:monocyte ratio (LMR) - have been shown to correlate with poor prognosis in multiple solid organ tumours. Analysis of CLARINET showed no significant association between NLR and progression-free survival.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Diakos C, Chan D, Gurney E, Bailey D, Barnes T,

Keywords: NLR, biomarker,

#1309 Dual 18F-Fluorodeoxyglucose/68Gallium DOTATATE (FDG/DOTA) PET Predicts Overall Survival in Neuroendocrine Tumours (NET)

Introduction: 68Ga-DOTATATE (DOTA) and FDG PET have been utilised in NETs to aid diagnosis, prognostication and guide management. FDG PET avidity is associated with poor prognosis, but the prognostic significance of dual FDG/DOTA grading has not been explored.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Chan D, Bailey D, Schembri G, Bernard E, Hsiao E,

Keywords: PET, prognosis,