Abstract Library

#4161 177Lu-DOTATATE (177Lu) efficacy in metastatic well-differentiated neuroendocrine tumors (wdNET): Differences in response according to metastases (met) location

Introduction: Treatment with 177Lu is standard of care for wdNET with high somatostatin receptor expression. Patterns of response could differ between hepatic (hep) and extrahepatic (ehep) met.

Conference:

Presenting Author:

Authors: Sánchez Gómez L, Guillén Sentís P, Ruffinelli J, Torrent F, Vercher Conejero J,

Keywords: 177lu-dotatate, well-differentiated neuroendocrine tumor, tumor growth rate,

#4112 Sexual dimorphism in small intestinal NETs: Any association with development of mesenteric metastases?

Introduction: Small-intestinal neuroendocrine tumors (SI-NET) are rising in incidence and complications such as mesenteric and hepatic metastases are associated with increased morbidity and mortality. It has recently been suggested that mesenteric metastases risk increases in women around menopause.

Conference:

Presenting Author: Castanho Martins M

Authors: Hassan D, Bally D, Castanho Martins M, Hodgetts H, Rombouts K,

Keywords: small intestine, mesenteric metastases, mesenteric fibrosis, sexual dimorphism, sex hormone,

#3742 Pancreatic neuroendocrine neoplasms – Epidemiological description, clinical and pathological aspects

Introduction: Pancreatic neuroendocrine neoplasms (PanNENs) are considered among the most aggressive, therefore an early diagnosis and proper management are major challenges globally. The incidence of PanNENs is rising as well as the unmet need to study their epidemiology.

Conference:

Presenting Author: Ciobanu O

Authors: Martin S, Ciobanu O, Herlea V, Fica S,

Keywords: pancreatic neuroendocrine neoplasm, epidemiology, clinical features, pathological aspects,

#3703 Impact of primary tumor resection and metastasectomy among gastroenteropancreatic neuroendocrine tumors with liver metastases only on survival

Introduction: The incidence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is increasing globally, and the patients are often diagnosed with synchronous liver metastases. Despite recommendations for primary tumor resection (PTR) with or without liver resection (LR) in the patients, there are conflicting data for their impact on overall survival (OS).

Conference:

Presenting Author: Chen Q

Authors: Chen Q, Li K, Rhodin K, Bartholomew A, Lidsky M,

Keywords: Gastroenteropancreatic neuroendocrine tumor, Liver metastasis, Resection, Prognosis, National Cancer Database,

#3445 The epidemiology of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in the North-East of England and a systematic review of literature

Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are rare, slow-growing malignancies with unknown aetiology and an increasing incidence was observed globally. With limited research on GEP-NET epidemiology, the reasons behind incidence disparities across countries remain unclear. Whether this increase was a true phenomenon or confounded by factors including diagnostic advancement, environment, and classification evolution needs further enquiry.

Conference:

Presenting Author:

Authors: Chu G, Robinson S, Etherson K, McNally R,

Keywords: Gastroenteropancreatic neuroendocrine tumor, Epidemiology, Incidence,