Abstract Library
Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.
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ENETS Abstract Search
#4345 Real-life results of the treatment with lutetium in advanced neuroendocrine tumours
Introduction: Therapy using lutetium-177 dotatate (177LU) was approved in Europe in 2017 for the treatment of advanced neuroendocrine tumours (NETs). Since then, it has become part of the strategies for treating NETs, making it now possible to evaluate real-life results.
Conference:
Presenting Author: Campos Ramírez S
Authors: Campos Ramírez S, Andrés A, Gómez Mugarza P, Blanco Abad C, Monreal Cepero M,
Keywords: Neuroendocrine tumour, Lutetium, Efficacy, Toxicity, Real-Word Evidence,
Introduction: Neuroendocrine neoplasms (NENs) consist of neuroendocrine tumours and neuroendocrine carcinomas, which are rare malignancies found in various anatomical sites, including the gastrointestinal tract, pancreatic islets, lungs, and adrenal glands. Poorly differentiated NECs are classified as high-grade carcinomas that bear resemblance to small-cell lung cancer; however, these patients experience a high risk of relapse and demonstrate a limited response to additional systemic therapies. Adrenocortical carcinoma (ACC) is another rare cancer and currently, no targeted therapies have demonstrated significant effectiveness for this condition. Preclinical investigations have indicated that Delta-like non-canonical notch ligand 1 (DLK1) is expressed in various neuroendocrine neoplasms, including ACC, SCLC, neuroblastoma, pheochromocytoma, and paraganglioma.
Conference:
Presenting Author: Del Rivero J
Authors: Del Rivero J, Glod J, Magee T, Cooper K, Rivero A,
#4184 Cystic Pancreatic Neuroendocrine Tumors: Rare but more common?
Introduction: Pancreatic neuroendocrine neoplasms uncommonly present as cystic lesions. Biological features of cystic pancreatic neuroendocrine tumors (cpNET) remain unclear.
Conference:
Presenting Author:
Authors: Blanco Cuso L,
Keywords: cystic neuroendocrine tumor, surgery,
#3469 Hedgehog pathway implications in gastroenteropancreatic neuroendocrine tumors
Introduction: Hedgehog (Hh) signaling pathway has a known role in the development of various tumors and we have selective inhibitors. However, its implications in neuroendocrine tumors (NETs) are still to be unrevealed.
Conference:
Presenting Author:
Authors: Saiz-Lopez P, Alcaraz R, Blanco-Abad C, Garcia-Toro E, Garcia-Girón C,
Keywords: Hedgehog, gastroenteropancreatic, prognostic,
#3070 Activity and Safety of Avelumab in Merkel Cell Carcinoma: Our Experience
Introduction: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine carcinoma of the skin. The use of checkpoint inhibitors has shown good results in the treatment of advanced MCC. Avelumab is a PD-L1 inhibitor able to prevent the inactivation of the T lymphocytes. We report a serie of consecutive MCC cases treated with Avelumab in two centres
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Giuffrida D
Authors: Puliafito I, Sciacca D, Bonasera A, Blanco G, Iacono F,