Abstract Library

#3435 Comparative characteristics of TTF-1 and SOX2 expression in neuroendocrine tumors of the lungs and thymus

Introduction: Neuroendocrine tumors of the lungs (NETLs) and thymus (NETTs) are a heterogeneous group of tumors. SOX2 is a key regulator of pluripotency induction, which is also involved in the mechanisms of carcinogenesis.

Conference:

Presenting Author:

Authors: Gurevich L, Bondarenko E,

Keywords: TTF-1, SOX-2, neuroendocrine tumor, lung, thymus,

#3315 Angiosarcoma is a rare and aggressive tumor of the Thyroid. Case Report

Introduction: Angiosarcoma(AS) of the thyroid gland is a rare(2-4% of all thyroid neoplasms) but highly malignant tumor with poor prognosis. AS showing endothelial differentiation. As most visceral ASs show epithelioid cell morphology, as well as co-expression of epithelial differentiation markers(keratins or EMA), the differential diagnosis with carcinomas is challenging. Given the importance of the correct histological diagnosis for therapy choice, this is a relevant issue

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Bondarenko E, Voronkova I, Gurevich L, Ashevscaya V, Fedorov D,

Keywords: Thyroid, Angiosarcoma, Epithelioid angiosarcoma,

#3138 Prognostic value of expression SOX2 in neuroendocrine tumors of different localization and degree of malignancy

Introduction: Overexpression of the SOX2 gene is related to its amplification and with the multiplication of the copy number at the 3q26.3 gene locus on chromosome 3. It has been shown that the SOX2 transcription factor is a key regulator of pluripotency induction; it is involved in the reprogramming of terminally differentiated somatic cells.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Gurevich L, Bondarenko E, Voronkova I, Ilovayskaya I, Ashevskaya V,

Keywords: SOX-2, neuroendocrine tumor, expression, prognostic factors,