Abstract Library
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#3862 DLL3 determination and immune milieu characterization in Neuroendocrine Neoplasms (NENs)
Introduction: High DLL3 expression in NENs may be used to activate the immune system by redirecting T cells via bispecific T cell engager (BITE) antibodies.
Conference:
Presenting Author:
Authors: Garcia Alvarez A, Serna G, Hernando Cubero J, Napoli S, Carmona Alonso A,
Keywords: Neuroendocrine, DLL3, Immunotherapy,
Introduction: General population interest in neuroendocrine tumors (NET) is influenced by mass-media news and awareness campaigns by advocacy and medical groups. Cases of NET in famous people greatly impact conversations about this disease.
Conference:
Presenting Author:
Authors: Hernando Cubero J, Garcia Alvarez A, Roca-Herrera M, Carmona Alonso A, Garcia Burillo A,
Introduction: Peptide receptor radionuclide therapy (PRRT) is a therapeutic strategy selected via a marker, somatostatin receptor (SSTRs) expression, with activity in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Its role in tumor sites outside the digestive tract remains unclear.
Conference:
Presenting Author:
Authors: Mitjavila Casanovas M, Carmona-Bayonas A, Bello P, de Matias Leralta J, Garcia Burillo A,
Keywords: 177Lu-DOTATATE, lung, neuroendocrine tumor, PRRT, pheochromocytoma, radionuclide therapy,
Introduction: The correlation between clinical benefit and toxicity is an unmet need in daily clinical practice. PRO-CTCAE is a questionnaire that allows subjective and detailed symptom reporting directly from patients. This prospective, multicentre study will apply PRO-CTCAE in a cohort of consecutive adult patients with metastatic NET on treatment with 177Lu.
Conference:
Presenting Author: Hernando J
Authors: Carmona Alonso A, Hernando Cubero J, Garcia Alvarez A, Roca-Herrera M, Garcia Burillo A,
Introduction: Peptide receptor radionuclide therapy (PRRT, Lu-177-DOTATATE) is safe and effective in neuroendocrine tumors (NET). However, the best sequence of administration is unknown.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Mitjavila Casanovas M, Carmona-Bayonas A, Pubul V, García-Cañamaque L, Aller J,
Keywords: Lu-177-DOTATATE, radionuclide, survival, treatment,