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Introduction: Etoposide-platinum (EP) chemotherapy has long stood as the reference treatment of grade 3 neuroendocrine neoplasms (G3 NEN). However, G3 NEN are heterogeneous, including well differentiated tumours (NET) and poorly differentiated carcinomas of large (LCNEC) or small (SCNEC) cell type, whose identification can be challenging and response to EP be very variable, usually low in NET.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Lacombe C, De Rycke O, Chen R, Colnot N, Hentic O,
Keywords: grade 3, chemotherapy, biomarkers, etoposide-platinum, pRb, p53,
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