Abstract Library

#1886 Effect of Treatment with Prolonged-Release Somatostatin Analogues on the Concentration of Serum Fibrosis Markers in Patients with Carcinoid Syndrome.

Introduction: A fibrosis is a major local and/or distant complication of neuroendocrine tumours (NETs) of the small intestine secreting serotonin. Tumour cells produce connective tissue growth factor CTGF and transforming growth factor TGFα and TGFβ which locally stimulate fibrosis and cause distant fibrosis.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Foltyn W, Zemczak A, Rosiek V, Kilian-Kita A, Kos-Kudła B,

Keywords: fibrosis,CTGF,TGFβ,carcinoid syndrome,

#1010 Soluble VCAM-1 and Its Relation to Clinical Staging and Histological Grading in Neuroendocrine Neoplasms (NENs)

Introduction: Cellular adhesion molecules play an important role in tumor progression and metastasis.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Rosiek V, Foltyn W, Strzelczyk J, Zemczak A, Kos-Kudła B,

Keywords: neuroendocrine neoplasms, sVCAM-1, histological grade, clinical stage,

#189 Matrix metalloproteinases (MMPs) and Tissue Inhibitors of Matrix Metalloproteinases (TMIPs) in GEP NET Patients – A Potential Prognostic Biomarkers for Metastases

Introduction: MMPs have the ability to degrade the extracellular matrix and are responsible for tumor invasion and metastases. Higher TIMP-1 levels are associated with low survival rate in some types of cancer.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Blicharz-Dorniak J, Kos-Kudla B, Foltyn W, Zemczak A, Rosiek V,

Keywords: gastroenteropancreatic tumors, MMPs, TIMP1, metastases,