Abstract Library

#4113 Establishment of a rat model of diarrhea induced by Surufatinib

Introduction: Surufatinib is a novel oral small-molecule TKI for the treatment of advanced neuroendocrine tumors. However, diarrhea is a common adverse event of surufatinib which can affects patients’ quality of life and clinical efficacy. Currently, there are no available animal models to study the cause and treatmen of surufatinib-related diarrhea.

Conference:

Presenting Author: Hu S

Authors: Hu S, Guo Y, Chen Y, Cheng Z, Deng C,

Keywords: Surufatinib, diarrhea, model, rat,

#4109 Digestive neuroendocrine tumors in the Mostaganémoise region (western Algeria)

Introduction: Digestive neuroendocrine tumors (NETs) are a group of rare tumors but whose incidence is increasing.They bring together different aspects in terms of location, clinical presentation, cell proliferation and tissue differentiation.

Conference:

Presenting Author: Zidane H

Authors: Zidane H, Kebbati Z, Chaalal M, Blidi I,

Keywords: digestive neuroendocrine tumor, abdominal pain, surgery, somatostatin analogues,

#3724 Tackling drug activity and resistance mechanisms in neuroendocrine tumors treated with cabozantinib

Introduction: Neuroendocrine tumors (NETs) are highly vascularized malignancies and angiogenesis plays a relevant role in cell proliferation and survival. Nowadays, innovative therapies have amplified the paradigm treatment of NETs. Among the compounds with anti-vascular properties, cabozantinib (CAB) appeared promising.

Conference:

Presenting Author: Cella C

Authors: Cella C, Cazzoli R, Fazio N, de Petro G, Gaudenzi G,

Keywords: Neuroendocrine tumor, angiogenesis, zebrafish model, mouse model.,

#2766 Neuroendocrine Neoplasms Arising in Inflammatory Bowel Disease: Clinical Features of 69 Cases and Literature Review

Introduction: An increased prevalence of neuroendocrine neoplasms (NENs) has been reported in patients with inflammatory bowel disease (IBD). However, we know little about IBD complicating NENs.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Hu P, Bai J, Liu M, Tang Q,

Keywords: crohn’s disease, ulcerative colitis, neuroendocrine neoplasms, intestinal flora, immunity,

#2301 Trends in Management of Gastro-Intestinal Neuroendocrine Tumors in Inflammatory Bowel Diseases: The Contribute of a Case Series.

Introduction: The risk to develop gastro-intestinal malignancies is higher in patients affected by inflammatory bowel diseases (IBD). Apart from colo-rectal cancer, related to a long standing inflammation, there is a growing evidence of neuroendocrine tumors (NETs) in these patients and a correlation between these two diseases has been postulated. We report four cases of NETs in IBD.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Rizza S

Authors: Rizza S, Canavese G, Ribaldone D, Cassoni P, Astegiano M,

Keywords: Neuroendocrine tumor, NET, inflammatory bowel disease, Chromogranin, Echo-endoscopy, EUS, IBD,