Abstract Library
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ENETS Abstract Search
#3004 Development of Anti-SSTR CAR T Cells for Future Treatment of NETs
Introduction: NETs overexpress somatostatin receptors (SSTRs).
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: Cives M
Authors: Mandriani B, Cives M, Pelle' E, Quaresmini D, Ramello M,
Keywords: CAR T cells, adoptive cellular immunotherapy, NETs,
Introduction: The prognosis for pts with PD-EP-NEC is poor.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author: McNamara M
Authors: McNamara M, Swain J, Craig Z, Wadsley J, Wall L,
Keywords: poorly differentiated, neuroendocrine carcinoma, second line treatment, docetaxel, liposomal irinotecan, 5-fluorouracil,
Introduction: High-grade gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs, G3) are aggressive cancers of the digestive system with poor prognosis and survival. Platinum-based chemotherapy (cisplatin/carboplatin +etoposide) is considered standard first-line palliative treatment. Etoposide is frequently administered intravenously, however oral etoposide is often used as an alternative. Concerns for oral etoposide include decreased bioavailability, inter- & intrapatient variability and patient compliance.
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author: Ali A
Authors: Ali A, Grönberg M, Hjortland G, Grønbæk H, Ladekarl M,
Keywords: chemotherapy, Neuroendocrine Neoplasms, Intravenous, Oral, survival,
Introduction: Biochemical diagnosis of endogenous hyperinsulinemic hypoglycemia is straightforward. Surgical removal of an insulinoma is hampered by difficulties to localize it using conventional radiological procedures. In vitro data suggest that human insulinoma cells exhibit a high density of GLP-1R. 111In-exendin-4 is an 111In labeled GLP-1R agonist that binds with high affinity to GLP-1R and may be helpful in localizing insulinomas.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Christ E, Forrer F, Wild D, Clerici T, Braendle M,
Keywords: insulinoma, GLP-1 receptor imaging,
Introduction: A phase II study was designed to assess the activity and safety of metronomic oral capecitabine, bevacizumab, and octreotide (Xelbevoct) in metastatic well-to-moderately differentiated neuroendocrine neoplasms (WMD-NEN). We also assessed the predictive role for progression free survival (PFS) of hypertension, proteinuria and vascular endothelial growth factor (VEGF) polymorphisms and the predictive role of vitamin D on proteinuria and PFS.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Brizzi M, Fazio N, Ferrero A, Nobili E, Volante M,
Keywords: bevacizumab,