Abstract Library

#1708 STREET - Somatostatin Treatment Experience Trial

Introduction: Somatostatin analogs (SSA) delay progress and decrease symptoms in patients with gastroenteropancreatic neuroendocrine tumours (GEP-NETs). It is not known whether patients’ experiences of injection treatment differ between different SSAs.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Almquist M, Myrenfors P, Ström T, Kozlovacki G,

Keywords: somatostatin analogs, octreotide, lanreotide, quality of life, injection,

#1337 O6-Methylguanine DNA Methyltransferase (MGMT) Deficiency and Response to Aranoza-Based Therapy in Patients with Neuroendocrine Tumors

Introduction: Aranoza (3-α-L-arabinopyranosyl-1-methyl-nitrosourea) – nitrosourea derivative, as STZ. O6-methylguanine DNA methyltransferase (MGMT) is an enzyme implicated in chemotherapy resistance to alkylating agents and its low levels are associated with sensitivity to them.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Polozkova S, Stepanova E, Delektorskaya V, Kozlov N, Gorbunova V,

Keywords: aranoza, MGMT, chemotherapy, NETs,

#493 Pasireotide and Octreotide LAR Was an Effective Combination in a Patient with Small Intestinal NET with Hypokalemia and a High Level of VIP

Introduction: Small Intestinal neuroendocrine tumors (NET) are argentaffin-positive tumors that progress slowly.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Kozlovacki G, Welin S, Eriksson B, Granberg D, Gaasvik-Blomqvist L,

Keywords: pasireotide, octreotide LAR, small intestinal NET, diarrhea, VIP ,

#437 mTOR Expression in Primary Pancreatic Neuroendocrine Tumors and their Metastases

Introduction: The mammalian target of rapamycin (mTOR), an important regulator of cell proliferation and invasion, is activated in pancreatic neuroendocrine tumors (PNETs). Information on detailed expression of mTOR in locally advanced or metastatic PNET is poorly described.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Kozlov N, Pavlovskaya A,

Keywords: neuroendocrine, pancreatic, tumor, metastases, p-mTOR, immunohistochemistry,

#178 Treatment with 177Lutetium-DOTA-Tyr3-octreotate in Patients with Neuroendocrine Tumors

Introduction: Neuroendocrine tumors express somatostatin receptors. Treatment with radiolabelled somatostatin analogs has been used for more than 10 years. Useful isotopes are 111Indium, 99Yttrium and 177Lutetium.

Conference: 8th Annual ENETSConcerence (2011)

Presenting Author:

Authors: Granberg D, Sandström M, Sundin A, Welin S, Kozlovacki G,

Keywords: NETs, Lutetium, radiolabelled somatostatin analogs, PRRT,