Abstract Library

#4063 Analysis of the NET G3 of lungs

Introduction: There are still a lot of questions regarding NET G3 subgroup and especially with lungs origin. Neuroendocrine neoplasms account for 20% of lung primary with only 2% for well-differentiated tumors.

Conference:

Presenting Author: Evdokimova E

Authors: Evdokimova E, Markovich A, Delektorskaya V, Yemelyanova G, Kuznetsova A,

Keywords: NET, G3, SSTR, somatostatin analogues, SSA, lung,

#3702 The role of the somatostatin analogues in large cell neuroendocrine carcinomas treatment

Introduction: Large cell neuroendocrine carcinoma (LCNEC) is still a poorly studied disease with low somatostatin receptors expression, so we have scant data on the effectiveness of the somatostatin analogues (SSA) in this disease.

Conference:

Presenting Author: Evdokimova E

Authors: Evdokimova E, Artamonova E, Delektorskaya V, Yemelyanova G, Markovich A,

Keywords: NEC, SSTR, somatostatin analogues, large cell carcinoma, SSA, LCNEC, somatostatin receptor,

#3191 Determination of somatostatin receptors types 2A and 5 (SSTR-2A, SSTR-5) expression in neuroendocrine tumors (NETs) and neuroendocrine carcinoma (NECs) of various localizations and grade

Introduction: One of the main treatment options for this disease is SA,which bind SSTRs to the on the surface of neuroendocrine cells (NC) and block them.But SSTRs are not always present in NC

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Emelianova G, Artamonova E, Ushakov A, Delektorskaya V, Markovich A,

Keywords: neuroendocrine tumor, neuroendocrine carcinoma, somatostatin receptor,

#3151 Immunohistochemical evaluation of vimentin aberrant expression in lung carcinoid tumors

Introduction: The carcinoid tumors of lung represent a rare group of epithelial well-differentiated neuroendocrine neoplasms with common morphological characteristics and highly variable clinical course. Vimentin is a type III intermediate filament that is involved in cell migration and adhesion. Vimentin also drives epithelial to mesenchymal transition (EMT) and metastasis in solid tumors. However, no information exists for vimentin expression levels and the characterization of EMT phenotypes of lung carcinoid tumors.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Delektorskaya V, Chemeris G, Smirnova E,

Keywords: lung carcinoid tumor, vimentin, immunohistochemistry, diagnosis,

#2821 Nucleophosmin Expression and Relocation in Pancreatic Neuroendocrine Tumors: Preliminary Data

Introduction: Pancreatic neuroendocrine tumors (PanNETs) are a heterogeneous group of neoplasms with unpredictable clinical course and biological behavior. Nucleophosmin (NPM) is an important multifunctional protein mainly located in the nucleolus. NPM has been reported to be overexpressed in many types of human cancer, activating tumor development and progression. However, the role of NPM in PanNETs is unknown.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Delektorskaya V, Bukaeva I, Ponomareva M, Smirnova E,

Keywords: neuroendocrine tumor, pancreas, nucleophosmin, immunohistochemistry, prognosis,