Abstract Library
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ENETS Abstract Search
Introduction: Cellular retinoic acid binding protein-I (CRABP-I), a member of the lipid-binding proteins family, plays an important role in retinoic acid-mediated cell proliferation and is essential for the development of various malignant neoplasms. The actual role of CRABP-I in tumor progression remains unknown.
Conference: 11th Annual ENETSConcerence (2014)
Presenting Author:
Authors: Delektorskaya V, Chemeris G, Zborovskaya I,
Keywords: neuroendocrine tumor, lung, immunohistochemistry,
Introduction: Assessment of liver metastases biology features associated with cell proliferation and adhesion has a strong prognostic impact in patients with gastroenteropancreatic (GEP) neuroendocrine carcinomas.
Conference: 8th Annual ENETSConcerence (2011)
Presenting Author:
Authors: Delektorskaya V, Chemeris G, Pavlovskaya A,
Keywords: Ki-67 labeling index, beta-catenin, neuroendocrine carcinomas, liver metastases, immunohistochemistry,
Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP NETs) comprise a heterogeneous group of neoplasm with different histological patterns and biological behavior. Only limited information is available on immunohistochemical prognostic factors of disease. Alterations in the cell-cell adhesion system are closely associated with cell invasion and metastasis in many malignancies, including those of endocrine origin. Abnormal expression of E-cadherin and beta-catenin has been reported to play an important role in these processes. Caveolin-1 has recently been identified as a tumor metastasis modifier factor, which might increase the cell metastasis potential through the interaction with E-cadherin. However, the role of caveolin-1 in GEP NETs cell invasion remains unknown.
Conference: 7th Annual ENETSConcerence (2010)
Presenting Author:
Authors: Delektorskaya V, Chemeris G,
Keywords: immunohistochemistry, E-cadherin, beta-catenin, caveolin-1, cyclin D1, Ki67, gastroenteropancreatic neuroendocrine tumors, metastasis,