Abstract Library

#4655 A novel nonpeptide drug conjugate (NDC) for the treatment of somatostatin receptor 2-expressing tumours

Introduction: Somatostatin receptor 2 (SST2) is an established target for the treatment of NETs and potentially other solid tumours.

Conference:

Presenting Author:

Authors: Zhao J, Sturchler E, Yang B, Chen M, Tang Y,

Keywords: somatostatin, solid tumour, drug conjugate, internalisation, cytotoxicity,

#4593 Excellent response to Ac-225 DOTATATE therapy in a patient with small cell lung cancer

Introduction: Peptide receptor radionuclide therapy (PRRT) is a validated treatment for patients with NETs overexpressing somatostatin receptors (SSTR). IHC analysis indicates that up to 50% of small cell lung cancer (SCLC) tumours are SSTR2 positive and thus can be targeted by SSR imaging and PRRT. Therapy with α-emitting radionuclides, such as Ac225, may offer several advantages over β-emitters by having higher energy transfer and more effective cancer cell death.

Conference:

Presenting Author: Tuncel M

Authors: Tuncel M, Türkan C, Eryılmaz Y, Pala A, Kılıçkap S,

Keywords: Ac-225 DOTATATE, Small Cell lung cancer, PET, somatostatin receptor, PRRT,

#4351 Outcomes of lobar and sub-lobar resection for lung neuroendocrine tumours (LNETs, carcinoids) – An ENETS CoE experience

Introduction: LNETs are rare tumours accounting for 1–2% of all lung cancers.

Conference:

Presenting Author:

Authors: Hojerat R, Idaiss I, Aviel G, Korach A, Bel-Ange A,

Keywords: lung neuroendocrine tumour, pulmonary carcinoid, lobar resection, sub-lobar resection, pro-gastrin-releasing peptide,

#4344 The deadly connection: Liver metastasis and prognostic factors in SCLC

Introduction: Patients with liver metastasis of small cell lung cancer (SCLC-LM) have a poor prognosis due to rapid recurrence and progression.

Conference:

Presenting Author: Ding J

Authors: Zou X, Huang X, Wang J, Liu J, Xie C,

Keywords: Small cell lung cancer, liver metastasis, prognostic factor, molecular mechanisms, bioinformatics analysis,

#4326 An evaluation of the methodological quality of published guidelines for the surgical treatment of pulmonary carcinoids

Introduction: Leading societies have established guidelines that vary significantly regarding recommendations for surgical management of pulmonary carcinoids (PC).

Conference:

Presenting Author: Bertolaccini L

Authors: Bertolaccini L, Bardoni C, Caffarena G, Chiari M, Diotti C,

Keywords: Neuroendocrine, lung cancer, surgery, AGREE 2, methodology, guidelines,