Abstract Library

#4178 MEN1 syndrome across four generations

Introduction: MEN1 should be suspected in patients with an endocrinopathy of two of the three typically affected organs, or with an endocrinopathy of one of these organs and a first-degree relative affected by MEN1 syndrome. Still, a delay in diagnosis occurs in most cases.

Conference:

Presenting Author:

Authors: Ciobanu O, Martin S, Muha M, Fica S,

Keywords: MEN1 syndrome, large kindred, case series,

#3340 Development and launch of first Australian accredited GP NET education course

Introduction: In 2018-19, NeuroEndocrine Cancer Australia (NECA) encouraged NET patients to nominate GP’s to fill in a 21-question survey. Questions ranged from diagnosis, initial symptoms, interactions with specialists, educational gaps & preferences. With only 5% of GPs suspecting a NET, these results provided the foundations for much needed education for GPs.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Cummins M

Authors: Cummins M, Leyden S,

Keywords: general practitioner, net education modules,

#3145 Reduction of serum insulin levels and diazoxide doses as an effect of PRRT in patients with severe hypoglycemia due to primary non-operative insulinoma

Introduction: Severe hypoglycaemia in a course of inoperable insulinoma may be life-threating and it is not always well controlled even by high doses of diazoxide, which in some cases cause a significant toxicity. Nowadays, other forms of effective therapy are not available - use of protein kinase inhibitors (everolimus, sunitynib) sometimes bring satisfactory effect but is often associated with the risk of serious side effects. Use of Peptide receptor radionuclide therapy (PRRT), characterized by relatively low toxicity, is not widely used.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Opalińska M

Authors: Opalinska M, Sowa-Staszczak A, Al Maraih I, Kostecka-Matyja M, Hubalewska-Dydejczyk A,

Keywords: PRRT, insulinoma, NEN,

#2285 The Role of Magnetic Resonance Imaging and Endoscopic Ultrasound Imaging in the Diagnosis and Management of Pancreatic Neuroendocrine Tumors (pNET) in Patients with Multiple Endocrine Neoplasia Type 1 (MEN1)

Introduction: Pancreatic neuroendocrine tumors (pNETs) in patients with Multiple Endocrine Neoplasia Syndrome type 1 (MEN 1) are frequently multiple and occur with an incidence that varies from 30-80% in different series. Magnetic Resonance Imaging (MRI) and techniques such as endoscopic ultrasound (EUS) are useful tools for tumor localization, size assessment and follow-up.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Tsoli M, Alexandraki K, Angelousi A, Karoumpalis I, Kolomodi D,

Keywords: pancreatic, neuroendocrine, MEN1, MRI, EUS,

#2076 Pancreatic Neuroendocrine Tumor in Polish Population with MEN 1 Syndrome

Introduction: The multiple endocrine neoplasia type 1 (MEN 1) is a genetically conditioned syndrome which is characterised by usually mild parathyroid and pituary gland adenomas, pancreatic neuroendocrine tumor (pNET). The last appear in 30-70% of MEN 1 patients being main life-threatening manifstation among MEN 1 patients. The prognosis might improve by presymptomatic tumor detection.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Soczomski P, Jurecka-Lubieniecka B, Rogozik N, Grajewska-Ferens M, Michalik B,

Keywords: Multiple endocrine neoplasia, Menin, Pancreatic Neuroendocrine Tumor, Polish population,