Abstract Library

#4421 Head-to-head comparison of 18F-AlF-NOTA-JR11 PET/MR and 68Ga-DOTATATE PET/CT in patients with neuroendocrine tumours: A prospective study

Introduction: PET/MR combines the molecular advantages of PET with excellent morphologic and anatomic delineation of MRI.18F-AlF-NOTA-JR11, a novel SSTR antagonist with a high affinity for SSTR2, has the potential to perform better than SSTR agonists in neuroendocrine tumour imaging.

Conference:

Presenting Author: Yu J

Authors: Jin X, Xie Q, Lu M, Li J, Yang Z,

Keywords: neuroendocrine tumour, PET/MR, SSTR antagonist, 18F-AlF-NOTA-JR11,

#3814 Intra-individual comparison of 68Ga-DOTATATE PET/CT and PET/MR

Introduction: Somatostatin receptor (SSTR) PET is a cornerstone of modern NET management and is used for (re)staging and PRRT selection. Next to PET/CT, hybrid PET/MR is now available for hybrid imaging of NETs.

Conference:

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Lens G, Vandecaveye V, Grauwels S, Deckers W,

Keywords: 68Ga-DOTATATE, PET/CT, PET/MR,

#3808 Comparison of [18F]AlF-NOTA-JR11 with [68Ga]DOTA-JR11 PET/MRI in models, mice, and neuroendocrine tumor patients

Introduction: Compared with [68]Ga, [18]F has the advantages of high production yield, shorter positron range, and favourable half-life allowing for centralized production and distribution to distant centers.

Conference:

Presenting Author: Yu J

Authors: Ding X, Meng X, Xie Q, Yu J,

Keywords: [18F]AlF-NOTA-JR11, [68Ga]DOTA-JR11, neuroendocrine tumor, PET/MRI,

#3147 Synthesis, preclinical evaluation and a pilot clinical imaging study of [18F]AlF-NODA-JR11 for neuroendocrine neoplasms compared with [68Ga]Ga-DOTA-TATE

Introduction: [68Ga]Ga (87% β+, 0.83Mev, T1/2=68min) is widely used associate with SSTR agonist and antagonist in molecular imaging of NETs. [18F]F (97% β+, 0.64Mev, T1/2=109min) has suitable half-life for peptide and lower β+-trajectory (

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author: Yu J

Authors: Yu J, X Q, Lu M, Li J, Y Z,

Keywords: neuroendocrine neoplasm, somatostatin receptor, [18F]AlF, JR11, TATE, PET imaging,

#2959 Synergic Value of 68Ga-DOTATOC PET and MRI in NET Patients Undergoing Simultaneous 68Ga-DOTATOC PET/MRI Scan

Introduction: The simultaneous acquisition of 68Ga-DOTATOC PET and functional MRI has relevant implication in the field of Neuroendocrine Tumours (NETs).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Mapelli P, Ironi G, Partelli S, Andreasi V, Muffatti F,

Keywords: 68Ga-DOTATOC, PET/MRI, NET, staging, restaging,