Abstract Library

#2863 Introduction of Dosimetry on PRRT Practice. A Useful Tool to Detect Responders and Evaluate Treatment Safety

Introduction: PRRT is a recognized salvage option for G1-G2 GEPNET. Currently, the Italian protocol (Lutathera AIFA Guidelines) consists in four fixed-dose of 177 Lu-DOTATATE. The dosimetry has recently been recognized as an important tool to guide PRRT but is not yet part of routine practice.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: SCALORBI F

Authors: Scalorbi F, Mazzaglia S, Maccauro M, Chiesa C, Prinzi N,

Keywords: prrt, healthy tissue and target lesion dosimetry, gastroenteropancreatic neuroendocrine tumor,

#2784 Predictive Factors of Tumor Recurrence after Radical Surgery for Gastro-Entero-Pancreatic Neuroendocrine Neoplasms (GEP-NENs): Identification of High-Risk Subgroups

Introduction: There is no proven role for adjuvant medical therapy after curative surgery (R0) for GEP-NENs.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Rossi R

Authors: Rossi R, Altomare M, Monteleone M, Prinzi N, Pusceddu S,

Keywords: radical surgery, recurrence, gastro-entero-pancreatic neuroendocrine neoplasms, prognostic factors,

#2700 Pancreatic Neuroendocrine Neoplasms and Liver Metastases: When Size Matters

Introduction: Small non-functioning pNENs are low grade indolent tumors, however distant metastases have also been documented in this subset of patients

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Monteleone M, Rossi R, Altomare M, Prinzi N, Cattaneo L,

Keywords: Pancreatic neuroendocrine neoplasia, Liver metastases,

#1729 Outstanding Response to Sunitinib in a Patient with Unresectable Retroperitoneal Paraganglioma

Introduction: Pheochromocitomas and Paragangliomas (PCs/PGLs) are rare neuroendocrine tumors arising from the adrenal medulla and extra-adrenal ganglia. Around 30-40% of these neoplasms are genetically determined. PCs/PGLs arising from the sympathetic chain can synthesize bioactive amines leading to typical syndromes, in contrast to parasympathetic PGLs that are mainly non-secretory.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Pusceddu S

Authors: Prinzi N, Femia D, Lo Russo G, Vernieri C, Concas L,

Keywords: Paragangliomas, Sunitinib,

#1726 A Long-Term Complete Response (CR) of Avelumab in Patient (pt) with Advanced Merkel Cell Carcinoma (MCC)

Introduction: MCC is a rare and aggressive cutaneous neuroendocrine cancer linked to exposure to the Merkel Polyomavirus (MCPyV). Cisplatin and VP16 chemo may be an effective treatment for metastatic MCC, but responses are often transient. The blockade of programmed death 1 (PD-1) immune inhibitory pathway by avelumab, an anti-PD-L1 checkpoint inhibitor, is being investigated in solid neoplasms. This strategy can also be of interest in MCC because these tumors often express PD-L1

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Pusceddu S

Authors: Femia D, Prinzi N, Vernieri C, Lo Russo G, Concas L,

Keywords: Merkel cell carcinoma, Avelumab,