Abstract Library

#4152 Valvular surgery in carcinoid heart disease – Indications and outcome

Introduction: Neuroendocrine tumors (NET) can release biogenic amines that can induce a fibrotic process in the heart valves known as carcinoid heart disease (CHD). Valvular replacement surgery is the standard of care, but such interventions are associated with significant morbidity and valid criteria for both selecting patients (pts) and timing of surgery are limited.

Conference:

Presenting Author:

Authors: Sponheim J, Beitnes J, Dahle G, Åvitsland T, Thiis-Evensen E,

Keywords: carcinoid heart disease, valvular surgery, prognostic factors,

#4147 5-Hydroxymethylcytosine profiling of plasma-derived circulating free DNA in patients with pancreatic neuroendocrine tumors treated with [177Lu]Lu-DOTA-TATE

Introduction: Cell-free DNA (cfDNA) 5-hydroxymethylcystosine (5hmC) analysis, a novel epigenomic technology, can detect changes in tumor gene expression and regulation in liquid biopsies.

Conference:

Presenting Author:

Authors: Sponheim J, Wong C, Thiis-Evensen E, Coruh C, Ning Y,

Keywords: [177Lu]Lu-DOTA-TATE, Lutathera, Peptide Receptor Radionuclide Therapy, Radioligand Therapy, Pancreatic Neuroendocrine Tumor, Biobank, 5-Hydroxymethylation,

#3866 Treatment efficacy in 212 metastatic small intestinal neuroendocrine tumor grade 2 patients

Introduction: Small intestinal neuroendocrine tumors (Si-NET) are frequently studied as a single entity, irrespective of their grade, which is known to influence prognosis.

Conference:

Presenting Author: Papantoniou D

Authors: Papantoniou D, Grönberg M, Thiis-Evensen E, Sorbye H, Landerholm K,

Keywords: small intestinal neuroendocrine tumor, grade 2, somatostatin analogues, PRRT, Ki-67, somatostatin-receptor negative,

#3638 Incidence of neuroendocrine neoplasms in Norway

Introduction: The incidence of neuroendocrine neoplasms (NENs) has been reported to increase over the last decades. The prevalence of NENs has to a lesser extent been reported.

Conference:

Presenting Author:

Authors: Thiis-Evensen E, Cetinkaya R,

Keywords: Neuroendocrine neoplasm, incidence, prevalence, neuroendocrine tumor, neuroendocrine carcinoma,

#3474 The prevalence of neuroendocrine neoplasms in Norway

Introduction: Neuroendocrine neoplasms (NEN) are a heterogeneous group of tumors originating from neuroendocrine cells comprising of neuroendocrine tumors (NET) and neuroendocrine carcinomas (NEC).

Conference:

Presenting Author:

Authors: Thiis-Evensen E, Åvitsland T, Sponheim J,

Keywords: Prevalence, incidence, neuroendocrine neoplasm, neuroendocrine tumor, neuroendocrine carcinoma, epidemiology,