Abstract Library
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#4122 Effectiveness and safety of surufatinib in treating pheochromocytomas and paragangliomas
Introduction: Pheochromocytomas and paragangliomas (PPGLs), classified as malignant by WHO in 2017, are partly catecholamine-secreting neuroendocrine tumors (NET). The 5-year overall survival rate of metastases PPGLs (mPPGL) is only between 50% and 60%. Surufatinib, approved for the treatment of NET, with anti-angiogenic and immunomodulatory properties, offers potential as a potential candidate for treating mPPGL.
Conference:
Presenting Author:
Authors: Su T, Zhong X, Song Q, Wang W,
Keywords: Pheochromocytomas and paragangliomas, treatment, Surufatinib,
Introduction: Pancreatic neuroendocrine neoplasms(NENs) are classified into neuroendocrine tumors (NET) G1, G2, G3, and neuroendocrine carcinoma (NEC), which are different pathogenesis. The two kinds of tumors that occurs in the same lesion in one patient is very rare. We found high grade neuroendocrine neoplasms(NENG3) with a diameter of 0.1 cm in a patient with a pancreatic NETG2 (1.7 cm in diameter). The cells were significant atypia with Ki67 index of 60%, focal necrosis, while metastatic nodules in the liver (12, 0.1-1.1 cm in diameter) were all high grade NENG3.
Conference: 17th Annual ENETSConcerence (2020)
Presenting Author:
Authors: Shi Y, Zhong D, Li Y, Niu Y, Tan H,
Keywords: pancreatic neuroendocrine neoplasms, whole exon sequencing, TRIOBP signaling pathway, MDM4,
Introduction: To investigate the clinical characteristics and prognostic factors of patients with gastric mixed adenoneuroendocrine carcinoma(MANEC).
Conference: 15th Annual ENETSConcerence (2018)
Presenting Author:
Authors: Bei X,
Keywords: gastric MAENC, neural invasion, lymph node involvement, prognosis,
Introduction: Colorectal neuroendocrine tumors (NETs) are a group of heterogenous neoplasm.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author:
Authors: Leng J, Li Z, Li Y, Chen Z, Li J,
Keywords: colorectal neuroendocrine tumors, WHO classification, long-term outcome,