Abstract Library

#4413 Efficacy and safety of adjuvant peptide receptor radionuclide therapy after curative surgery of locoregional limited small intestine neuroendocrine neoplasia (APSIN) – A multi-centre, prospective, randomised, controlled, phase III study

Introduction: Our multi-centre, prospective, open-label, two-arm parallel group, randomised, controlled, phase III study will address the efficacy and safety of adjuvant peptide receptor radionuclide therapy after curative surgery of locoregional limited small intestine neuroendocrine neoplasia.

Conference:

Presenting Author: Eilsberger F

Authors: Eilsberger F, Luster M, Rau J, Avci H, Schade-Brittinger C,

Keywords: adjuvant therapy, neuroendocrine neoplasia, small intestine, peptide receptor radionuclide therapy, PRRT,

#4248 Tryptophan pathway metabolites as prognostic biomarkers of recurrent disease in curatively operated neuroendocrine tumor patients

Introduction: The majority of NET patients experience recurrent disease after curative surgery. There is a need for prognostic biomarkers in this patient group.

Conference:

Presenting Author: Johansen S

Authors: Johansen S, Hansen T, Goll R, Florholmen J,

Keywords: Plasma Tryptophan Metabolites, Prognostic Biomarker, Recurrent Disease after Curative Surgery,

#3623 Characteristics of clinical features of MEN1-associated and sporadic insulinomas – One clinical center experience

Introduction: Insulinomas are usually small, benign tumors that can be radically treated surgically. They may occur as sporadic or be associated with hereditary syndromes, (mainly MEN1 syndrome). In such cases, they may differ in clinical presentation including risk of recurrence and dissemination after curative surgery, which translates into long-term therapy effects.

Conference:

Presenting Author:

Authors: Opalinska M, Gilis-Januszewska A, Morawiec-Sławek K, Kurzyńska A, Sowa-Staszczak A,

Keywords: MEN1, insulinoma, sporadic insulinoma, MEN1 insulinoma,

#3584 Nodal recurrence after curative surgery for non-functioning pancreatic neuroendocrine tumors: A retrospective cohort study

Introduction: Nodal recurrence occurs in a significant proportion of patients submitted to curative surgery for non-functioning pancreatic neuroendocrine tumors (NF-PanNETs). However, its determinants have been poorly investigated.

Conference:

Presenting Author: Peralta Ferreira M

Authors: Peralta Ferreira M, Andreasi V, Muffatti F, Crippa S, Tamburrino D,

Keywords: pancreatic neuroendocrine tumor, curative surgery, nodal recurrence, distant recurrence, number of positive lymph nodes,

#3352 Exacerbation of Necrolytic Migratory Erythema after 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy

Introduction: Necrolytic migratory erythema (NME) is an uncommon skin disorder which is characterized by deep erythematous plaques with superficial blistering, erosions and crusts. NME is a cutaneous manifestation of glucagonoma. Glucagonoma syndrome is a paraneoplastic disease, caused by an excessive secretion of glucagon by pancreatic alpha cells.

Conference:

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Vanden Bulcke A, Curvers S, de Haes P, de Hertogh G,

Keywords: glucagonoma, necrolytic migratory erythema, PRRT, 177Lu-DOTATATE, neuroendocrine tumor, pancreas,