Abstract Library

#3658 Effects of curcumin on pancreatic neuroendocrine neoplasms

Introduction: Pancreatic neuroendocrine neoplasms (pNENs) are a group of rare tumors with strong heterogeneity. Recently, its incidence has gradually increased, which brought a great challenge of treatment because of lack of management for this rare disease.

Conference:

Presenting Author:

Authors: Li Y, Tian C, Cheng Z, Han D, Guo Y,

Keywords: pancreatic neuroendocrine neoplasm, curcumin, PI3K, AKT, mTOR pathway,

#3596 Molecular mechanism of curcumin inhibiting proliferation of pancreatic neuroendocrine tumor cells

Introduction: Studies have shown that curcumin regulates malignant tumors through many important signalling pathways, such as Ras, P13K, p53, AKT, mTOR, Wnt-catenin, etc. Regarding the research on the molecular target mechanism of curcumin inhibiting pancreatic neuroendocrine tumors, there is a lack of relevant data at home and abroad. The proven antitumor potential targets of curcumin were intersected with the proteins present in pancreatic neuroendocrine tumor QGP-1 cells, and AKT/mTOR was selected as the central content of this study.

Conference:

Presenting Author: Han D

Authors: Han D, Du H,

Keywords: Curcumin, Pancreatic neuroendocrine tumor cells, Mechanism,

#3595 Effects of curcumin on proliferation of pancreatic neuroendocrine tumor cells

Introduction: Medical studies have shown that curcumin has the effects of lowering blood lipids, anti-tumor, anti-inflammatory, choleretic and antioxidant. In recent years, domestic and foreign studies have reported that curcumin has an increasingly prominent effect on inhibiting the proliferation of tumor cells, but the effect of curcumin on pancreatic neuroendocrine tumor cells has not been studied.

Conference:

Presenting Author: Han D

Authors: Han D, Du H,

Keywords: Curcumin, Pancreatic Neuroendocrine Tumor, Cells, Inhibitors,