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#3754 Real-world data regarding the obesity paradox in patients with gastroenteropancreatic (GEP) NENs in a single centre in the United Kingdom

Introduction: The obesity paradox is a hypothesis showing patients (pts) with obesity have a prolonged overall survival compared to the ones with a normal weight. This paradox is present in multiple types of gastrointestinal cancer. In one population-based study from the USA, this paradox is also present in pts with GEP-NENs. However real-world data for the UK are lacking.

Conference:

Presenting Author: Clement D

Authors: Clement D, Brown S, Dolly S, Kibriya N, Howard M,

Keywords: gep-nen, survival, bmi, obesity paradox,

#979 Characteristics and Treatments of Patients with G3 Gastroenteropancreatic Neuroendocrine Tumors (G3-NET) and Neuroendocrine Carcinoma (NEC): A European Multicenter Retrospective Study

Introduction: Data on G3-NET and NEC are limited. No standard therapy following platinum-etoposide failure is established and first-line therapy in G3-NET is not codified.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Heetfeld M, Rinke A, Borbath I, Crespo G, Olsen I,

Keywords: gastrointestinal cancer, neuroendocrine carcinoma, grade 3 NET, Ki-67, chemotherapy,