Abstract Library

#3744 Germline whole-exome sequencing of patients with neuroendocrine neoplasms reveals pathogenic or likely pathogenic variants in a large subset of patients

Introduction: The germline predisposition to neuroendocrine neoplasms (NEN) is not-well understood beyond genetic syndromes associated with MEN1 loss.

Conference:

Presenting Author: Sukrithan V

Authors: Sukrithan V, Boateng I, Jain P, Liyanarachchi S, Buss J,

Keywords: whole exome sequencing, germline, population, mutyh, pkd1, atp4a, pah,

#3712 Germline pathogenic variants in patients with high-grade gastroenteropancreatic neuroendocrine neoplasms

Introduction: High-grade gastroenteropancreatic (HG-GEP) neuroendocrine neoplasms (NEN) are aggressive cancers with a dismal prognosis. The molecular etiology remains poorly characterized and prevalence of pathogenic germline variants unknown.

Conference:

Presenting Author: Sorbye H

Authors: Sorbye H, Venizelos A, Perren A, Couvelard A, Hjortland G,

Keywords: germline, mutations, gastropancreatic, neuroendocrine carcinoma, NET G3, high-grade,

#2816 Germline Variants in Cancer Predisposing Genes in Young Adults with Neuroendocrine Tumors

Introduction: Advances in genomics have enabled the recognition of new cancer predisposing genes (CPG). There are few studies of CPG in neuroendocrine tumors (NET).

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Riechelmann R

Authors: Riechelmann R, de Paula C, Donadio M, Barros M, Formiga M,

Keywords: hereditary syndrome, neuroendocrine tumors, germline variants,