Abstract Library

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#1723 Evaluation of the Somatostatin and CXCR4 Chemokine Receptor Expression in Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NEN) of Different Origin

Introduction: Somatostatin receptors (SSTR) are known for their overexpression in well-differentiated GEP-NEN, whereas the chemokine receptor CXCR4 is considered to be present mainly in highly proliferative and advanced tumors.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Lupp A

Authors: Mai R, Kaemmerer D, Sänger J, Neubauer E, Schulz S,

Keywords: somatostatin receptor, CXCR4,

#1347 Evaluation of the Somatostatin, CXCR4 Chemokine and Endothelin A Receptor Expression in a Large Series of Paragangliomas

Introduction: Paragangliomas are predominantly benign tumors, but in some cases invasive growth and also metastasis is observed. Given the limited number of nonsurgical treatment options, novel target structures for diagnostics and therapy of this tumor entity are urgently needed.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Kaemmerer D

Authors: Kaemmerer D, Sänger J, Arsenic R, D'Haese J, Neumann J,

Keywords: paraganglioma, somatostatin, CXCR4,

#689 Immunohistochemical Expression of Somatostatin Receptors 1, 2, 3, and 5 Types (SSR) in Functioning and Non-Functioning Gastroenteropancreatic Neuroendocrine Tumors

Introduction: SSRs are therapeutic targets for the somatostatin analogues in treatment of gasrtroenteropancreatic neuroendocrine tumors (GEP-NET).

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Gurevich L, Kazantseva I, Panteleeva E, Britvin T, Egorov A,

Keywords: neuroendocrine, tumors, somatostatin, receptor,

#657 Correlation of Monoclonal and Polyclonal Somatostatin Receptor (SSTR) 5 Antibodies in Pancreatic Neuroendocrine Tumors

Introduction: For a few years now, highly specific monoclonal antibodies have been available to characterize neuroendocrine tumors for somatostatin-receptor (SSTR) expression.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author: Peter L

Authors: Kaemmerer D, Lupp A, Peter L, Fischer E, Schulz S,

Keywords: somatostatin, pancreatic tumor, neuroendocrine tumor, monoclonal antibody, UMB-4,

#446 Comparative Expression Analysis of Somatostatin Receptor Subtypes in Human Neuroendocrine Tumors Using Two Sets of New Monoclonal Antibodies

Introduction: Expression of somatostatin receptor subtypes (sstr) is required for the successful use of somatostatin analogues (SSA) in the treatment of neuroendocrine tumors (NET). Reliable detection of sstr could improve the selection of SSA treatment. Rabbit and mouse monoclonal antibodies (mAbs) were recently developed independently in Jena and Basel.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Lambertini C, Nuciforo P, Schulz S, Schmid H,

Keywords: sstr, NET, sstr-specific mAb,