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#3812 Validation of NEP-D score as a prognostic index in bronchial carcinoid tumors
Introduction: The development of prognostic scores able to classify patients with Bronchial Carcinoid (BC) according to clinical outcomes may help guide treatment selection. The NEP- score was found to be useful to stratify survival probability in patients with well-differentiated neuroendocrine neoplasms (NENs). According to multiple factors (age, primary tumor site, presence of metastasis, Ki-67, presence of functioning status and prior surgical removal of the primary tumor) NEP- score stratifies patients into different risk groups. The NEP-score at diagnosis (NEP-D score) is a derived score that could be calculated at diagnosis and does not consider the appearance of new metastases during follow-up.
Conference:
Presenting Author:
Authors: Medici M, Gagliardi I, Zanata I, Borges de Souza P, Ambrosio M,
Keywords: Bronchial Carcinoid, Neuroendocrine neoplasm, NEP-Score, Prognosis, Survival,
Introduction: The prognosis of atypical carcinoids (AC) is worse than that of typical carcinoids (TC). Molecular analyses have suggested a more heterogeneous disease for the first ones. However, no previous study has established an individualized predictive model for the prognosis of lung neuroendocrine tumos (Lu-NETs) considering the location of the primary tumor in the right versus left lung parenchyma.
Conference:
Presenting Author: La Salvia A
Authors: La Salvia A, Marcozzi B, Manai C, Mazzilli R, Pallocca M,
Keywords: Lung neuroendocrine tumor, Tumor location (left vs right parenchyma), Prognostic factor, Nomogram, R-ache-L Prognostic Score,
Introduction: Absence of relevant prognostic score (PS) in NET
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Pusceddu S
Authors: Pusceddu S, Barretta F, Botta L, Trama A, Milione M,
Keywords: neuroendocrine, prognostic score,
Introduction: Prognostic markers for risk-stratification of GI-NECs are lacking.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Lamarca A
Authors: Lamarca A, Barriuso J, McNamara M, Hubner R, Valle J,
Keywords: NEC, score, overall survival, high grade, prognostic,
Introduction: In PanNET tumors contradictory data about the prognostic role of MGMT (O6-methylguanine DNA methyltransferase) has been published. NDRG-1 (N-myc downstream-regulated gen-1) and PHLDA-3 (Pleckstrin homology-like domain family A member 3) immunohistochemistry (IHC) expressions have been evaluated in several solid malignant tumors, but their roles in PanNET remain unknown
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Viudez A
Authors: Viudez A, Carvalho F, Maleki Z, Zahurak M, Laheru D,
Keywords: Pancreatic Neuroendocrine Tumor, MGMT, NDRG-1, PHLDA-3,