Abstract Library

#4569 Dramatic response to tarlatamab in a patient with metastatic primary small cell neuroendocrine carcinoma of the breast

Introduction: Primary small cell neuroendocrine carcinoma of the breast (SCNCB) is a rare malignancy with a poor prognosis. Tarlatamab, a DLL3-targeted bispecific T-cell engager, is FDA-approved for extensive-stage small cell lung carcinoma.

Conference:

Presenting Author: Patel D

Authors: Patel D, Alahmadi A, Maddocks K, Lampert B, Giglio P,

Keywords: tarlatamab, small cell neuroendocrine carcinoma of the breast,

#4422 A case report of an undifferentiated neuroendocrine carcinoma with an unknown primary site

Introduction: In the situation where the primary lesion remains unknown, high-grade poorly differentiated neuroendocrine carcinoma typically shows extensive metastasis at the time of clinical visit. Common metastatic sites include the liver, bones, lungs and brain, and the prognosis is extremely poor.

Conference:

Presenting Author:

Authors: Lv J, Tang Y,

Keywords: poorly differentiated neuroendocrine carcinoma, unknown primary origin,

#3449 Cavum neuroendocrine carcinoma

Introduction: Small cell neuroendocrine carcinoma of the head and neck is an unusual entity, especially in the cavum, given their rarity and the lack of randomized trials. The therapeutic management of these tumors is difficult. Their prognosis remains unfavourable.

Conference:

Presenting Author:

Authors: Aris H, Ghomari S,

Keywords: Small cell neuroendocrine carcinoma, Cavum,

#3113 Small cell neuroendocrine carcinoma of vagina - Rare, aggressive but curable?

Introduction: Small cell neuroendocrine carcinoma (SCNC) is a highly proliferative disease. It commonly affects lung and only 2.5-5% are extrapulmonary. SCNC of vagina is very rare with only 32 published cases in English literature.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Godinho J, Simões P, Leal-Costa L, Baptista C, Casa-Nova M,

Keywords: small cell neuroendocrine carcinoma, vagina, highly proliferative, rare disease,

#3089 Mixed Large and Small Cell Neuroendocrine Carcinoma of the Endometrium: A Case Report and Literature Review

Introduction: Neuroendocrine carcinoma (NEC) is an extremely rare subtype of endometrial cancer which is usually seen among perimenopausal or postmenopausal women. It runs an aggressive course and posts a clinical challenge due to limited treatment options available.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Cruz M

Authors: Cruz M, Uyboco J,

Keywords: neuroendocrine carcinoma, endometrium,