#3048
Somatostatin Analogs or Active Surveillance in Sporadic Non-Functioning Pancreatic Neuroendocrine Tumors
Introduction:
Non-functioning (NF), sporadic pancreatic neuroendocrine tumors (pNETs) have usually an indolent behavior, but sometimes show an unpredictable aggressiveness. Surgery is the first-choice for localized tumors >2 cm. Unresectable or metastatic lesions expressing somatostatin receptors (SSTRs) are treated with Somatostatin analogs (SSAs). No evidence of SSAs efficacy exists in tumors ≤2 cm, for which active surveillance has been proposed.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Schinzari G,
Maiorano B,
Rossi E,
Bianchi A,
Chiloiro S,
Keywords:
pNET,
non-functioning,
sporadic,
somatostatin analogs,
surveillance,
#3022
Diagnostic Accuracy of 68Gallium Positron Emission Tomography (68Ga PET), Endoscopic Ultrasound (EUS) and Computed Tomography in the Assessment of Lymphnode Metastases by Nonfunctioning Pancreatic Neuroendocrine Neoplasms
Introduction:
The presence of nodal metastasis is one of the most important predictive factors for recurrence after radical surgery for nonfunctioning Pancreatic Neuroendocrine Neoplasms (NF-PanNEN). Nevertheless, it is not clear which is the best diagnostic examination to identify preoperatively lymphnodal metastasis.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Giannone F
Authors:
Giannone F,
Muffatti F,
Partelli S,
Andreasi V,
Guarneri G,
Keywords:
imaging,
lymph node,
metastases,
#2982
Comprehensive Molecular Analysis Identifies Driver Mutations in Metastases of Sporadic Well-Differentiated Neuroendocrine Tumours of the Small Intestine
Introduction:
Small intestinal neuroendocrine tumours (SI-NETs) represent a heterogenous group of tumours. The molecular mechanisms which contribute to progression of SI-NETs are poorly elucidated. They are considered to be molecularly distinct from neuroendocrine carcinomas (NECs), which share oncogenic pathways with adenocarcinomas.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Samsom K
Authors:
Samsom K,
van Veenendaal L,
Roepman P,
Kodach L,
Steeghs N,
Keywords:
whole genome sequencing,
neuroendocrine tumour,
small intestine,
genetics,
#2972
Characteristics and Management of Paragangliomas, 10 Years Experience
Introduction:
Paraganglioma (PG) is a rare extra-adrenal neuroendocrine tumor, with common sites of presentation being abdomen, and head and neck region. The majority of PGs appear to be sporadic. However, almost half of cases are associated with an inherited syndrome. The highest malignancy rates are seen in paragangliomas (PGs) associated with SDHB mutations, which are usually abdominal and secretory.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Sardo E,
Cameselle-Garcia S,
Casteras A,
Toledo R,
Acosta D,
Keywords:
Paraganglioma,
SDHB mutations,
Functioning Tumors,
