#2982
Comprehensive Molecular Analysis Identifies Driver Mutations in Metastases of Sporadic Well-Differentiated Neuroendocrine Tumours of the Small Intestine
Introduction:
Small intestinal neuroendocrine tumours (SI-NETs) represent a heterogenous group of tumours. The molecular mechanisms which contribute to progression of SI-NETs are poorly elucidated. They are considered to be molecularly distinct from neuroendocrine carcinomas (NECs), which share oncogenic pathways with adenocarcinomas.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Samsom K
Authors:
Samsom K,
van Veenendaal L,
Roepman P,
Kodach L,
Steeghs N,
Keywords:
whole genome sequencing,
neuroendocrine tumour,
small intestine,
genetics,
#2977
Predicting Survival in Patients with a Neuroendocrine Tumor of the Small Intestine (SI-NET)
Introduction:
SI-NET comprise the largest group of neuroendocrine tumors. Because of their heterogeneity, predicting survival has proven challenging. A nomogram (NG) to assess SI-NET disease specific survival (DSS) has been developed in 2010 by Modlin, et al. based on analysis of retrospective data from the Surveillance, Epidemiology and End Results (SEER) database.
Conference:
17th Annual ENETSConcerence (2020)
Presenting Author:
Authors:
Levy S,
van Veenendaal L,
Korse C,
Verbeek W,
Vriens M,
Keywords:
SI-NET,
Nomogram,
Survival,
#2252
Safety and Efficacy of TAE and SIRT in NET Patients
Introduction:
Transarterial embolization (TAE) and Selective Internal Radiation Therapy (SIRT) are used for treating patients with liver metastases of a neuroendocrine tumour (NET). However, the safety and effectiveness of TAE and SIRT have scarcely been compared.
Conference:
15th Annual ENETSConcerence (2018)
Presenting Author:
Authors:
Van Veenendaal L,
Braat A,
Meier M,
Samsom K,
Verbeek W,
Keywords:
neuroendocrine tumor,
liver metastases,
therapy,
radioembolization,
transarterial embolization,
safety,
efficacy,