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#3567 Metastatic mixed VIPoma/PPoma-induced diarrhoea causing renal failure
Introduction: Pancreatic neuroendocrine tumors (pNETs) are rare, but despite better prognosis than other pancreatic tumors, their presentation is often occult. VIPomas are a further subtype secreting vasoactive intestinal peptide (VIP). Associated symptoms are particularly non-specific, with watery diarrhoea and electrolyte disturbance which mimics less sinister pathology. Consequently, this presentation is often overlooked resulting in tumor progression and delayed diagnosis, hindering effective management.
Conference:
Presenting Author: Monaghan A
Authors: Monaghan A, Brown G, Takhar A,
Keywords: Pancreatic Neuroendocrine Tumor, Neuroendocrine Tumor, pNET, Vasoactive Intestinal Peptide, VIPoma, Pancreatic Polypeptide,
Introduction: No study has yet assessed the utility of biochemical biomarkers for evaluating NET burden using 68Ga-DOTATATE PET/CT.
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author:
Authors: Tirosh A, Papadakis G, Millo C, Sadowski S, Herscovitch P,
Keywords: PET burden,
Introduction: New clinical prognostic tools are needed in order to select patients with NETs that are at higher risk of DSM. Biochemical biomarker DT is used clinically for prognosis prediction in several solid malignancies
Conference: 14th Annual ENETSConcerence (2017)
Presenting Author: Tirosh A
Authors: Tirosh A, Nilubol N, Patel D, Kebebew E,
Keywords: doubling time, biomarker, prognosis,
Introduction: VIPoma is a rare neuroendocrine tumor (NET) with a high potential to develop hepatic metastases and poor prognosis. The primitive tumor is non-symptomatic and usually localized within the pancreas. Liver metastasis drove the prognosis and induced profuse watery diarrhea or renal failure.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Coriat R
Authors: Dréanic J, Lepère C, Mostafa E, Gouya H, Rougier P,
Keywords: vipoma, hepatectomy, Trans Arterial Chemo Embolization (TACE), neuroendocrine tumors (NET), vasoactive intestinal peptide (VIP), systemic chemotherapy,
Introduction: Small Intestinal neuroendocrine tumors (NET) are argentaffin-positive tumors that progress slowly.
Conference: 9th Annual ENETSConcerence (2012)
Presenting Author:
Authors: Kozlovacki G, Welin S, Eriksson B, Granberg D, Gaasvik-Blomqvist L,
Keywords: pasireotide, octreotide LAR, small intestinal NET, diarrhea, VIP ,