Abstract Library

#2940 Avelumab in Unresectable/Metastatic, Progressive, Poorly Differentiated, Grade 3 Neuroendocrine Carcinomas (NECs)

Introduction: Poorly differentiated, G3 NECs are associated with poor outcomes and have no effective treatment options apart from cytotoxic chemotherapy.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Rodriguez-Freixinos V

Authors: Rodriguez-Freixinos V, Chan D, Doherty M, Wasson K, Iscoe N,

Keywords: Poorly differentiated, G3 NECs, Avelumab, Immunotherapy,

#2248 High Grade (G3) Gastro-Entero-Pancreatic Neuroendocrine Neoplasms: Should the New WHO Classification Apply to All?

Introduction: Grade 3 (G3) neuroendocrine neoplasms (NEN), arising from the gastro-entero-pancreatic system (GEP), are classified according to WHO 2010 and defined as having a Ki67 of > 20%. However this groups together G3 well differentiated neuroendocrine tumours (WD-NET) with poorly differentiated neuroendocrine carcinomas (PD-NEC). Recently, WHO have proposed a new classification for pancreatic NEN, with sub-division into G3 WD-NET and G3 PD-NEC

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Furnace M

Authors: Furnace M, Muller G, Rundell C, Shah R, Luong T,

Keywords: G3, well-differentiated, poorly differentiated, Ki-67,

#2211 Clinicopathologic Characteristics of Chinese Patients with Gastroenteropancreatic Neuroendocrine Neoplasms: Results of a Nation-Wide Retrospective Epidemiology Study

Introduction: he rare incidence of gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) has contributed to a paucity of large epidemiologic studies of patients with this condition, especially in China.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Yu P, Chi Y, Shi S, Chen Y, Jiang L,

Keywords: gastroenteropancreatic neuroendocrine neoplasms, clinicopathological characteristics, immunohistochemical staining,

#2045 Perioperative Outcomes of Surgery for Pancreatic Neuroendocrine Neoplasms in Germany

Introduction: The incidence of pancreatic neuroendocrine neoplasms(pNEN) is increasing and the perioperative outcomes of specialized centers are favourable.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Mintziras I, Werner J, Keck T, Hommann M, Germer C,

Keywords: pancreatic neuroendocrine neoplasms, surgical resection, StuDoQ|pancreas registry,

#1911 Histological Differentiation Provides Useful, Additive and Independent Prognostic Information to Proliferation Index in G2 and G3 Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs)

Introduction: The WHO 2010 classification has provided a valuable tool to stratify NEN prognosis based on an objective measure, the proliferation index. However, morphology and, in particular, tumor differentiation, is emerging again as a relevant feature that should not be dismissed due to its important clinical implications.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: García Carbonero R

Authors: Sánchez Cánovas M, Nuñez B, Benavent M, Teulé A, Segura A,

Keywords: WHO 2010 classification,