18F-FDG PET/CT-avid discordant volume as a biomarker in patients with gastroenteropancreatic neuroendocrine neoplasms – A multicentre study

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Introduction: Dual 18F-FDG and 68Ga-DOTATATE PET/CT is emerging as a powerful technique to predict tumor biology. Whilst the presence of discordant disease (FDG avid/DOTA non-avid) predicts poor prognosis, it remains unknown whether the volume of discordant disease is also a significant predictor.

Aim(s): To determine if discordant tumor volume predicts prognosis in patients with advanced gastroenteropancreatic neuroendocrine neoplasms (GEPNEN).

Materials and methods: Multicentre retrospective study in patients with advanced GEPNEN and paired FDG and DOTATATE PET/CT

Conference:

Presenting Author: Chan D

Authors: Chan D, Hayes A, Karfis I, Conner A, Mileva M,

Keywords: prognostic biomarker, PET imaging, 18F-FDG, 68Ga-DOTATATE, dual PET, discordance,