Epidemiology of neuroendocrine neoplasms (NEN) in England 2012-2018 – Home location, incidence and survival including access to neuroendocrine centres of excellence (CoE)

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Introduction: Many cancers have been associated with environmental factors but these remain unexplored for NEN. Travel to and from a CoE can be a significant burden to patients. There is evidence that this impacts on treatment outcomes and survival in other cancers.

Aim(s): To demonstrate associations between NEN incidence, survival and environmental factors via a population based geospatial approach; to evaluate the relationship between distance to their nearest CoE and survival.

Materials and methods: A retrospective population-based study using data (2012-2018) from the National Cancer Registry and Analysis Service. Using geographical information software, patients’ locations were mapped to identify areas with high NEN density. Environmental cancer exposures were also examined. Euclidian distances (ED) between patient location and nearest CoE were calculated and compared with overall survival (OS).

Conference:

Presenting Author: Nwoguh C

Authors: Nwoguh C, Chandrakumaran K, White B, Russell B, Handford J,

Keywords: neuroendocrine, access to care, neuroendocrine neoplasm, incidence, geospatial, mapping, geographic, survival, environmental factors,