Multivisceral Transplantation and Vascularised Sentinel Forearm Flap for a Metastatic Gut-Derived Neuroendocrine Tumour: Follow-up
Introduction: We previously reported the first documented case of a novel approach in a patient with extensive mesenteric metastases from a small bowel (SB) NET: this combined multivisceral transplantation (MVT) and a vascularised sentinel forearm flap (VSFF) from the same donor.
Aim(s): We re-present this case after prolonged follow-up.
Materials and methods: A male patient was diagnosed with a well-differentiated Grade 1 (Ki67 <1%) NET when aged 44. Initial biochemistry was: chromogranin A 395pmol/L (normal <60), chromogranin B 349pmol/L (normal <150), 24hr urinary 5-HIAA 643 µmol/L (normal <40). Pre-operative 68-Ga DOTATATE PET/CT demonstrated uptake in an aorto-caval lymph node and bulky mesenteric disease, which was confirmed at laparotomy as stage IV disease encasing the mesenteric root. Numerous lymph nodes and multifocal primary tumour (7 sub-centimetre lesions) were also found at surgery.
Conference: 13th Annual ENETSConcerence (2016)
Presenting Author: Malczewska A
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