Role of endoscopic resection margin (R1) in the clinical outcome of patients with neuroendocrine neoplasia

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Introduction: Endoscopic resection margin R1 (ER1) describes neoplasia presence at lateral and/or deep margin. Highest rate of R1 resection occurs in duodenal NENs (d-NENs) where advanced resection techniques [endoscopic submucosal dissection (ESD); full thickness resection (EFTR)], are more difficult to apply. In gastric (g-NENs) and rectal NENs (r-NENs), due to favourable anatomy, ESD or EFTR obtain lower rates of R1 resection.

Aim(s): To assess endoscopic recurrence/progression risk at resection site in pts with gastric, duodenal and rectal NENs undergone endoscopic ER1.

Materials and methods: Retrospective multicenter study, g-NENs (type I, single/multiple), d-NENs (not ampullary, not functioning), r-NENs pts, all <2cm.

Conference:

Presenting Author: Marasco M

Authors: Marasco M, Massironi S, Campana D, Mosca M, Dell'unto E,

Keywords: neuroendocrine, endoscopy,