STZ-Based Chemotherapy is Associated with Durable Response Rate in Pancreatic NET as 1st or 2nd Line Treatment

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Introduction: The role of chemotherapy for pancreatic neuroendocrine tumors (pNETs) is controversially discussed. Objective response rates (RR) with streptozocin (STZ)-based chemotherapy are variable. Novel targeted drugs have recently been approved.

Aim(s): To evaluate the efficacy of STZ+5-Fluorouracil (5-FU) in a large pNET cohort.

Materials and methods: Data from 97 patients (pts) with advanced pNET were analysed retrospectively. Imaging was reviewed (RECIST criteria) by an experienced radiologist.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Dilz L

Authors: Dilz L, Denecke T, Arsenic R, Steffen I, Pape U,

Keywords: pancreatic NET, Ki-67, chemotherapy, streptozotocin,