Abstract Library

#2854 A Meta-Analysis of the Accuracy of a Neuroendocrine Tumor mRNA Genomic Biomarker (NETest) in Blood

Introduction: The lack of an accurate blood biomarker in neuroendocrine tumor (NET) disease impedes effective management.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Oberg K

Authors: Öberg K, Califano A, Strosberg J, Ma S, Pape U,

Keywords: NETest, Meta-analysis, biomarker, in vitro diagnostic, diagnostic, management, NET, AUC, ROC,

#2701 Assessing the Gaps in Experience and Knowledge of Australian Primary Health Care Professionals (GPs), in Treating and Caring for the Increasing Number of Australian Neuroendocrine Tumour (NET) Patients

Introduction: Conservatively,the incidence of NETs is 7 / 000' p.a, however,the prevalence of patients living with NETs is higher,40/000',making it the 2nd most common GI malignancy after colorectal cancer.Patients are living longer,however,with impaired quality of life.Management of debilitating symptoms such as diarrhoea,fatigue,anxiety,and flushing are complex and heterogenous.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author: Leyden S

Authors: Leyden S, Cummins M, Wakelin K,

Keywords: diagnosis, ongoing care, primary healthcare, NETs, quality of life, symptom management, NET symptoms,

#2289 Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Receptor Expression in Patients with Neuroendocrine Neoplasia

Introduction: Targeting the death receptor pathway of apoptosis represents a promising approach for the development of novel cancer therapeutics. TNF-related TRAIL induces apoptosis upon binding to TRAIL receptors 1 and 2 (TRAIL-R1/DR4 and TRAIL-R2/DR5). TRAIL-R3 (DcR1) and TRAIL-R4 (DcR2) have been reported to block TRAIL-mediated apoptosis upon overexpression. Specially agonists for the apoptosis-inducing TRAIL-R1 and TRAIL-R2 are currently tested in clinical trials.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Sättele R, Jann H, Fischer C, Pape U, Schefold J,

Keywords: TRAIL, apoptosis, NENs,

#2209 The ENETS Registry: First Results of a Collaborative Effort Including over 12.000 Patients with Neuroendocrine Neoplasms (NENs) from 7 European Countries

Introduction: NENs are rare and global European epidemiologic data are only based on national or compilation of national registries. So, there is a need for comprehensive homogenous information

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Borbath I

Authors: Borbath I, Pape U, Garcia-Carbonero R, Sedláčková E, Kollár A,

Keywords: ENETS registry, Europe,

#2171 A Matched-Pair Analysis of Conventional Surgical Methods versus Enucleation for Pancreatic Neuroendocrine Tumors

Introduction: Pancreatoduodenectomy and distal pancreatectomy are still main therapy for pancreatic neuroendocrine tumours (pNETs).Recently enucleation has also been increasingly used to treat pNETs.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author:

Authors: Mao W, Lv Y, Chen W, Han X, Zang L,

Keywords: neuroendocrine tumor, pancreatic neoplasms, surgery, prognosis,