Abstract Library

#1478 The Role of p27 in Pheochromocytoma Development

Introduction: The Cdkn1b gene, encoding p27, is a tumor susceptibility gene for multiple endocrine neoplasia syndromes in rats (MENX) and humans (MEN4) with development of pheochromocytoma (PCC), respectively. Recently, it was reported that p27 indirectly regulates gene transcription by associating with transcription factors (TF) and inhibiting gene transcription at specific promoters.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Richter A

Authors: Richter A, Lalli E, Sass S, Pellegata N,

Keywords: pheochromocytoma, p27, ChIP-Seq,

#1008 STZ-Based Chemotherapy is Associated with Durable Response Rate in Pancreatic NET as 1st or 2nd Line Treatment

Introduction: The role of chemotherapy for pancreatic neuroendocrine tumors (pNETs) is controversially discussed. Objective response rates (RR) with streptozocin (STZ)-based chemotherapy are variable. Novel targeted drugs have recently been approved.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Dilz L

Authors: Dilz L, Denecke T, Arsenic R, Steffen I, Pape U,

Keywords: pancreatic NET, Ki-67, chemotherapy, streptozotocin,