Abstract Library

#4569 Dramatic response to tarlatamab in a patient with metastatic primary small cell neuroendocrine carcinoma of the breast

Introduction: Primary small cell neuroendocrine carcinoma of the breast (SCNCB) is a rare malignancy with a poor prognosis. Tarlatamab, a DLL3-targeted bispecific T-cell engager, is FDA-approved for extensive-stage small cell lung carcinoma.

Conference:

Presenting Author: Patel D

Authors: Patel D, Alahmadi A, Maddocks K, Lampert B, Giglio P,

Keywords: tarlatamab, small cell neuroendocrine carcinoma of the breast,

#3814 Intra-individual comparison of 68Ga-DOTATATE PET/CT and PET/MR

Introduction: Somatostatin receptor (SSTR) PET is a cornerstone of modern NET management and is used for (re)staging and PRRT selection. Next to PET/CT, hybrid PET/MR is now available for hybrid imaging of NETs.

Conference:

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Lens G, Vandecaveye V, Grauwels S, Deckers W,

Keywords: 68Ga-DOTATATE, PET/CT, PET/MR,

#3352 Exacerbation of Necrolytic Migratory Erythema after 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy

Introduction: Necrolytic migratory erythema (NME) is an uncommon skin disorder which is characterized by deep erythematous plaques with superficial blistering, erosions and crusts. NME is a cutaneous manifestation of glucagonoma. Glucagonoma syndrome is a paraneoplastic disease, caused by an excessive secretion of glucagon by pancreatic alpha cells.

Conference:

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Vanden Bulcke A, Curvers S, de Haes P, de Hertogh G,

Keywords: glucagonoma, necrolytic migratory erythema, PRRT, 177Lu-DOTATATE, neuroendocrine tumor, pancreas,

#3329 The role of 68Ga-DOTATATE PET/CT in extensive IgG4-positive fibrosis surrounding a mesenteric lymph node metastasis of a neuroendocrine tumor: A case report

Introduction: IgG4 expression is commonly seen in mesenteric tumor deposits from small intestine neuroendocrine tumors leading to a dense fibrotic response which can simulate IgG4-related sclerosing mesenteritis in medical images, hereby impeding a correct diagnosis.

Conference: 18th Annual ENETS Concerence (2021)

Presenting Author:

Authors: Ahmadi Bidakhvidi N, Cuyle P, Sagaert X, Ballaux F, De Bruecker Y,

Keywords: small intestine neuroendocrine tumor, 68Ga-DOTATATE PET/CT, mesenterial lymph node, fibrosis, IgG4,

#2072 Peptide Receptor Radionuclide Therapy (PRRT) in Gastroenteropancreatic Grade 3 Neuroendocrine Neoplasms: A Retrospective International Multicenter Study

Introduction: Gastroenteropancreatic (GEP) grade 3 neuroendocrine neoplasms (NEN G3) are rare, highly malignant neoplasms with poor prognosis and limited therapeutic options. Median survival following chemotherapy is only 10-12 months.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Skovgaard D

Authors: Skovgaard D, Fazio N, Granberg D, Grozinsky-Glasberg S, Ahmadzadehfar H,

Keywords: neuroendocrine neoplasms, WHO grade 3, PRRT, Progression-free survival, Overall survival,