Abstract Library

#1548 Clinicopathological Features and Prognosis of Neuroendocrine Tumors: Analysis from a Single-Institution in Brazil

Introduction: In Brazil, information on neuroendocrine tumors (NET) is scarce. We summarized data in our center to increase knowledge of this disease in Brazilian population.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Silva M

Authors: Costa D, Albuquerque C, Ricardo E, Saito A, Boente L,

Keywords: neuroendocrine, epidemiology, prognosis,

#1544 Immunohistochemical Expression of Estrogen and Progesterone Receptors in Neuroendocrine Tumors

Introduction: Expression of progesterone (PR) and estrogen receptor (ER) in some neuroendocrine tumors (NET) raises the possibility of hormonal regulation in these tumors, but those prevalence and clinical implication are unknown.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Silva M

Authors: Costa D, Albuquerque C, Boente L, Araujo D, Fares A,

Keywords: progesterone, estrogen, carcinoid,

#898 Evaluation of Tumor Response to Targeted Therapies in Precision-Cut Slices of Human Pancreatic Neuroendocrine Tumors

Introduction: Patients with PNET might benefit from new therapeutic approaches acting on the mTOR signaling pathway. Culture of precision-cut slices could allow testing these molecules in human tumors, allowing personalized treatments.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Bucau M, Cros J, Rebours V, Albuquerque M, Paradis V,

Keywords: pancreas, targeted therapies, tissue culture, neuroendocrine tumors,

#536 Orexins Exert a Pro-Apoptotic Effect on Neuroendocrine Tumors (NETs) in an Ex Vivo Culture Model of Tissue Slices

Introduction: Ex vivo culture models of tissue slices are suitable to test the effect of antitumor agents in human tumors. The orexins are neuropeptides binding to G protein-coupled receptors (OX1-R and OX2-R), exerting a pro-apoptotic effect in human colon and pancreatic cancer cell lines.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Palazzo M, Rebours V, Voisin T, Albuquerque M, Paradis V,

Keywords: digestive NET, orexins, apoptosis, ex vivo model,