Abstract Library

#2127 Detection of Bone Metastases at FDOPA-PET in Small-Intestine (si)NET: Prevalence and Associated Factors

Introduction: FDOPA-PET has high sensitivity to detect siNET and associated metastases.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: de Mestier L

Authors: de Mestier L, Deleval N, Hentic O, Palazzo M, Lebtahi R,

Keywords: small intestine NET, bone metastases, PET, FDOPA-PET,

#1557 Dual High Throughput Proteomic and Transcriptomic Screen for Predictive Biomarkers of Everolimus Sensitivity in Pancreatic NET

Introduction: mTOR inhibitor Everolimus is approved for the treatment of well-differentiated PNET. The heterogeneity of the response rate and the potential toxicity warrant predictive biomarkers.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: CROS J

Authors: Bucau M, Cros J, Raffenne J, Rebours V, Palazzo M,

Keywords: PNET, everolimus, predictive biomarkers,

#1137 Contrast Harmonic Endoscopic Ultrasonography (CH-EUS) is Able to Predict Aggressivity in Pancreatic Neuroendocrine Tumors

Introduction: Pancreatic neuroendocrine tumors (PNET) are a heterogeneous group regarding malignancy.

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author:

Authors: Palazzo M, Palazzo L, Aubert A, Maire F, Fabre M,

Keywords: pancreatic neuroendocrine tumor, CH-EUS,

#889 Delayed Haematological Toxicity in Patients Treated with 177Lu-octreotate Peptide Receptor Radiotherapy (PRRT) for Metastatic Neuroendocrine Tumors (NETs)

Introduction: PRRT is associated with a high tumor control rate and early toxicity seems acceptable (haematological grade 3-4 toxicity: 11.3%). Long-term monitoring of haematological toxicity is unavailable.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author:

Authors: Hentic O, Lebtahi R, Kwekkeboom D, Fenaux P, Palazzo M,

Keywords: metastatic NET, PRRT, haematological toxicity,

#536 Orexins Exert a Pro-Apoptotic Effect on Neuroendocrine Tumors (NETs) in an Ex Vivo Culture Model of Tissue Slices

Introduction: Ex vivo culture models of tissue slices are suitable to test the effect of antitumor agents in human tumors. The orexins are neuropeptides binding to G protein-coupled receptors (OX1-R and OX2-R), exerting a pro-apoptotic effect in human colon and pancreatic cancer cell lines.

Conference: 9th Annual ENETSConcerence (2012)

Presenting Author:

Authors: Palazzo M, Rebours V, Voisin T, Albuquerque M, Paradis V,

Keywords: digestive NET, orexins, apoptosis, ex vivo model,