#4572
Steroid dosing to prevent tumour flare reaction with 177Lu-DOTATATE
Introduction:
Tumour flare reactions including increased pain and small bowel obstruction (SBO) have been reported in patients with somatostatin receptor (SSTR)-positive gastroenteropancreatic neuroendocrine tumours (GEP-NETs) receiving 177Lu-DOTATATE. Retrospective reviews report tumour flare reactions in 6 to 40 percent of high-risk patients receiving 177Lu-DOTATATE and report success with using corticosteroid prophylaxis to prevent tumour flare recurrence with subsequent doses of 177Lu-DOTATATE (Strosberg, et al., 2021; Salner, et al., 2020).
Conference:
Presenting Author:
Authors:
Cass A,
Skotte E,
Wheless M,
Stockton S,
Ramirez R,
Keywords:
177Lu-DOTATATE,
corticosteroid prophylaxis,
tumour flare,
#2301
Trends in Management of Gastro-Intestinal Neuroendocrine Tumors in Inflammatory Bowel Diseases: The Contribute of a Case Series.
Introduction:
The risk to develop gastro-intestinal malignancies is higher in patients affected by inflammatory bowel diseases (IBD). Apart from colo-rectal cancer, related to a long standing inflammation, there is a growing evidence of neuroendocrine tumors (NETs) in these patients and a correlation between these two diseases has been postulated. We report four cases of NETs in IBD.
Conference:
15th Annual ENETSConcerence (2018)
Presenting Author:
Rizza S
Authors:
Rizza S,
Canavese G,
Ribaldone D,
Cassoni P,
Astegiano M,
Keywords:
Neuroendocrine tumor,
NET,
inflammatory bowel disease,
Chromogranin,
Echo-endoscopy,
EUS,
IBD,