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#1520 Osteotropism of NETs: Role of the SDF1/CXCR4 Axis in Regulating EMT

Introduction: NETs metastasize to the bone in up to 20% of patients. The SDF1/CXCR4 axis is a key determinant of osteotropism, and we showed that NETs overexpressing CXCR4 are more likely to develop bone metastases.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Cives M

Authors: Simone V, Quaresmini D, D'Oronzo S, Rizzo F, Felici C,

Keywords: emt, cxcr4,