Abstract Library

#4466 Molecular characterisation of extrapulmonary mixed adeno-neuroendocrine neoplasms (MiNENs): The NIRVANA sub study

Introduction: Extrapulmonary (EP) mixed neuroendocrine/non-neuroendocrine neoplasms (MiNENs) are rare cancers with a dismal prognosis. The gene mutation profiles are incompletely understood.

Conference:

Presenting Author: Spada F

Authors: Spada F, Pisa E, Ranghiero A, Frassoni S, Bagnardi V,

Keywords: MiNEN, NGS, ESCAT, chemotherapy,

#4205 Precision medicine in advanced NENs: Molecular profiling and target actionability real world data

Introduction: Molecular profiling (MP) of NENs is not performed on routine basis and its potential clinical use is a matter of debate.

Conference:

Presenting Author: Farinea G

Authors: Farinea G, Anton-Pascual B, Catoya J, Modrego A, La Salvia A,

Keywords: Genomic Profiling, ESCAT, NEN, Precision Medicine,

#4163 Metabolite biomarker discovery for pancreatic neuroendocrine tumors using metabolomic approach

Introduction: Metabolic flexibility is one of the key hallmarks of cancer and metabolites are the final products of this adaptation, reflecting the tumors’ aberrant changes. However, the metabolic plasticity of pancreatic neuroendocrine tumors (pNET) is still unknown. pNETs are heterogeneous which makes their diagnosis, prognosis and therapeutic management difficult.

Conference:

Presenting Author:

Authors: Jannin A, Dessein A, Dabo S, Descat A, Vantyghem M,

Keywords: pancreatic NET, diagnostic biomarker, plasma metabolites, molecular pathways,

#3530 Molecular profiling and target actionability for precision medicine in neuroendocrine neoplasms: The Gustave Roussy experience

Introduction: Key molecular alterations (MA) of neuroendocrine neoplasm (NEN) of various grade/primaries have been described but the applicability of molecular profiling (MP) for precision medicine (PM) in NEN remains to be demonstrated.

Conference:

Presenting Author: Boilève A

Authors: Boilève A, Faron M, Bayle A, Mouren A, Lamartina L,

Keywords: Precision medicine, personalized treatment, neuroendocrine tumor, neuroendocrine carcinoma, molecular profile,

#955 Usefulness of the WHO Classification and of the ENETS TNM Staging System to Predict Prognosis in Patients with Rectal NENs

Introduction: WHO classification and TNM staging system have been proposed for rectal neuroendocrine neoplasia (NENs). However, their prognostic accuracy is not validated yet.

Conference: 11th Annual ENETSConcerence (2014)

Presenting Author: Pescatori L

Authors: Pescatori L, Gaujoux S, Capurso G, Couvelard A, Panzuto F,

Keywords: rectal NENs, survival, prognosis,