Abstract Library

Welcome to the open-access search for all ENETS abstracts presented at the Annual ENETS Conferences.

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ENETS Abstract Search

#4545 Analysis of the mutational landscape of pancreatic neuroendocrine tumours before and after temozolomide treatment

Introduction: Temozolomide (TMZ) is an alkylating agent and standard treatment for pancreatic neuroendocrine tumours (pNET). Resistance to TMZ may be acquired through inactivation of the mismatch repair system, leading to high tumour mutation burden (hTMB).

Conference:

Presenting Author: Trevisani E

Authors: Trevisani E, Borghesani M, Reni A, Agnoletto C, Luchini C,

Keywords: neuroendocrine, next generation sequencing, temozolomide, hypermutation, tumour mutational burden,

#3770 Molecular imaging, molecular profiling and outcomes in patients with transformation to grade 3 neuroendocrine neoplasia (NEN)

Introduction: Transformation of Grade (G) 1-2 to G3 NEN has prognostic & therapeutic implications, but its mechanisms are unclear.

Conference:

Presenting Author: Kong G

Authors: Kong G, Prall O, Flynn A, Tothill R, Hatzimihalis A,

Keywords: G3, transformation, IHC, genomic sequencing, FDG PET/CT, P53, Rb1, mutations,

#3649 Influence of pathogenic somatic mutations on the survival rates of patients with neuroendocrine tumors of the gastrointestinal tract (NET GI)

Introduction: Genomic sequencing of 40 tumors samples from patients diagnosed with NET GI was performed. Further, according to the results obtained, the survival rates of patients were evaluated.

Conference:

Presenting Author: Androsova A

Authors: Androsova A, Orlova R, Gordiev M, Ivanova A, Belyak N,

Keywords: NET, mutations, BRCA, POLE, Genomic sequencing,

#1440 Expression and Clinical Significance of Alpha-internexin in Gastroenteropancreatic Neuroendocrine Neoplasm

Introduction: Alpha-internexin is a 66-kDa neuronal intermediate filament protein, data on its role in gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) are limited.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author: Jie C

Authors: Yuhong W, Yuanjia C, Minhu C, Jie C,

Keywords: gastroenteropancreatic neuroendocrine neoplasm, alpha-internexin, prognosis, methylation,