Abstract Library

#4227 Evaluation of circulating extracellular vesicles as suitable prognostic markers in MEN1-associated non-functioning pancreatic neuroendocrine neoplasia

Introduction: Non-functioning pancreatic neuroendocrine neoplasias (NF-pNENs) significantly contribute to premature death of multiple endocrine neoplasia type 1 (MEN1) patients. Reliable prognostic markers for disease progression are lacking. Circulating liquid biomarkers, including microRNAs and Long-non-Coding (LnC) RNAs in extracellular vesicles, are emerging as new prognostic tools.

Conference:

Presenting Author:

Authors: Manoharan J, Khizanishvili N, Krasser-Gercke N, Albers M, Mintziras I,

Keywords: Multiple endokrine neoplasia type 1, Extracellular vesicles, Non-functioning pancreatic neuroendocrine neoplasia, exosomal-LnC-RNA NEAT1, exosomal miRNA451a,

#2150 Prognostic Value of Immunohistochemical Expression of Somatostatin Receptors (SS-R2 and SS-R5) in the Gastroenteropancreatic Neuroendocrine Tumors, Diagnosed in the University Hospital of Pleven, Bulgaria, from the Period 2010 to November 2017

Introduction: Sоmatostatin is a regulatory peptide with a variety of actions in normal and tumor cells. In recent years there are a lot of observations suggesting that the gastrointestinal neuroendocrine tumors (GEP-NETs) expressed somatostatin receptors (SS-R).The expression could be valuable for the prognosis of patients with GEP-NETs due to the research evidence that well-differentiated tumors express SS-R in the great majority of the cases.

Conference: 15th Annual ENETSConcerence (2018)

Presenting Author: Vladova P

Authors: Vladova P, Iliev S, Popovska S,

Keywords: gastroenteropancreatic neuroendocrine tumors, SS-R, prognostic value,

#1749 Changes in the Frequency and Epidemiology of the Gastroenteropancreatic Neuroendocrine Tumors, Diagnosed in the University Hospital of Pleven, Bulgaria from the Period 2010 to November 2016

Introduction: During the recent years there has been an observed tendency of increased frequency of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) all around the world due to the clinicians' improved knowledge about the diagnostic and treatment of these tumors. We have discovered a correlation between world tendency and the local tendency we have observed in the University Hospital of Pleven, Bulgaria from 2010 to November 2016.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author:

Authors: Vladova P, Iliev S, Popovska S,

Keywords: gep-nets,epidemiology, centers of excellence,

#1365 Exploring the Rising Incidence of Gastroenteropancreatic Neuroendocrine Tumors According to the Data from Regional Cancer Registry: A Population-Based Analysis of Epidemiology

Introduction: The incidence of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) is reported to arise worldwide. Similar tendency is observed in Bulgaria during the recent 6 years.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Vladova P, Popovska S, Iliev S, Tonchev P,

Keywords: gep-nets, incidence, regional cancer registry,

#750 Management of Metastatic Nonfunctional Pancreatic Neuroendocrine Tumor

Introduction: Nonfunctional NETs themselves present in generally two ways, either with symptoms caused by the tumor compression of other organs, or found by imaging test performed for other reasons.

Conference: 10th Annual ENETSConcerence (2013)

Presenting Author:

Authors: Egorov A, Vasiliev I, Gurevich L, Kondrashin S, Parnova V,

Keywords: pancreas, nonfanctional tumor, metastase,